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Ataciguat

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Catalog No. T21607Cas No. 254877-67-3
Alias HMR-1766

Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.

Ataciguat

Ataciguat

🥰Excellent
Purity: 99.09%
Catalog No. T21607Alias HMR-1766Cas No. 254877-67-3
Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
Pack SizePriceAvailabilityQuantity
1 mg41 €In Stock
5 mg88 €In Stock
10 mg139 €In Stock
25 mg282 €In Stock
50 mg419 €In Stock
100 mg606 €In Stock
1 mL x 10 mM (in DMSO)118 €In Stock
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Purity:99.09%
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Product Introduction

Bioactivity
Description
Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
In vitro
Ataciguat induces the relaxation in aortic rings or coronary rings. In the presence of nitric oxide synthase (NOS) inhibitor, the endothelium effect was abolished to DETA-NO or ataciguat, in both vessels. Ataciguat was able to induce NO production in HUVECs cells. In the presence of NOS inhibitor, the NO production induced by ataciguat was abolished[1].
AliasHMR-1766
Chemical Properties
Molecular Weight576.49
FormulaC21H19Cl2N3O6S3
Cas No.254877-67-3
SmilesN(S(=O)(=O)C1=CC=C(Cl)S1)C2=C(C(NC3=CC=C(S(=O)(=O)N4CCOCC4)C=C3)=O)C=C(Cl)C=C2
Relative Density.1.613 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 95 mg/mL (164.79 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7346 mL8.6732 mL17.3464 mL86.7318 mL
5 mM0.3469 mL1.7346 mL3.4693 mL17.3464 mL
10 mM0.1735 mL0.8673 mL1.7346 mL8.6732 mL
20 mM0.0867 mL0.4337 mL0.8673 mL4.3366 mL
50 mM0.0347 mL0.1735 mL0.3469 mL1.7346 mL
100 mM0.0173 mL0.0867 mL0.1735 mL0.8673 mL

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