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Gallopamil hydrochloride

Gallopamil hydrochloride
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Purity:99.02%
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Gallopamil hydrochloride

Catalog No. T11353LCas No. 16662-46-7
Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.
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Pack SizePriceAvailabilityQuantity
1 mg$32In Stock
5 mg$67In Stock
10 mg$92In Stock
25 mg$143In Stock
50 mg$193In Stock
100 mg$297In Stock
500 mg$728In Stock
1 mL x 10 mM (in DMSO)$83In Stock
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Product Introduction

Bioactivity
Description
Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.
In vitro
Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM[1].
In vivo
In male Wistar rats, Gallopamil hydrochloride (0.2 mg/kg; i.v. for 5 min) markedly reduces ventricular tachycardia and totally prevents fibrillation. Gallopamil hydrochloride significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate[2].
AliasMethoxyverapamil hydrochloride
Chemical Properties
Molecular Weight521.09
FormulaC28H41ClN2O5
Cas No.16662-46-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (115.14 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9191 mL9.5953 mL19.1905 mL95.9527 mL
5 mM0.3838 mL1.9191 mL3.8381 mL19.1905 mL
10 mM0.1919 mL0.9595 mL1.9191 mL9.5953 mL
20 mM0.0960 mL0.4798 mL0.9595 mL4.7976 mL
50 mM0.0384 mL0.1919 mL0.3838 mL1.9191 mL
100 mM0.0192 mL0.0960 mL0.1919 mL0.9595 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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