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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20936 | Lauramine oxide | LDAO,Dimethylaurylamine oxide,Refan,Lauryldimethylamine oxide | Antibacterial |
Lauramine oxide (Refan) is effective against common bacteria such as E. coli and S. aureus, however it is non-denaturing and may be used to solubilize proteins. | |||
T23636 | Adenosine N1-oxide | ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide | Immunology/Inflammation related |
Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock. | |||
T35366 | 4-Nitroquinoline 1-oxide | 4-Nitroquinoline 1-oxide,4Nqo,NQO,4-NQO,4-Nitroquinoline-N-oxide,NQNO | Others |
4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts of purine adducts. | |||
T0067 | Nicotinic acid N-oxide | Nicotinic acid 1-oxide,Oxiniacic Acid | Others |
Nicotinic acid N-oxide (Nicotinic acid 1-oxide) is a nicotinic acid derivative, used to treat hyperlipoidemia. | |||
T0621 | Diphenyl oxide | Oxydibenzene,Phenyl ether | Others |
Diphenyl oxide (Oxydibenzene) is used in the manufacture of spices and dyes. | |||
T37600 | Dasatinib N-oxide | Others | |
Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib.It is also a potential impurity in commercial preparations of dasatinib[1][2]. | |||
T9433 | Nickel(II) oxide | Others | |
Nickel(II) oxide is the chemical compound with the formula NiO. It is the principal oxide of nickel. | |||
T28231 | Olanzapine N-Oxide | Others | |
Olanzapine N-Oxide is a metabolite of Olanzapine which shows antipsychotic activity. | |||
T4462 | Roflumilast N-oxide | PDE | |
Roflumilast N-oxide is an inhibitor of PDE type 4. | |||
T38003 | Levofloxacin N-oxide | Others | |
Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide. | |||
T0636 | 4-Methylmorpholine N-oxide | Others | |
4-Methylmorpholine N-oxide is often used as a co-oxidant and sacrificial catalyst in oxidation reactions. | |||
T72112 | Clozapine N-oxide dihydrochloride | AChE | |
Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier.Clozapine N-oxide dihydrochloride induces activation of DR... | |||
T4494 | CLOZAPINE N-OXIDE | Dopamine Receptor , 5-HT Receptor , AChR , Drug Metabolite | |
Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopa... | |||
T19592 | Trimethoprim N-oxide | Trimethoprim 1-N-oxide | Others |
Trimethoprim N-oxide is a human urinary metabolite. | |||
T19593 | Trimethoprim 3-oxide | Trimethoprim 3-N-oxide | Others |
Trimethoprim 3-oxide trimethoprim primary metabolite. | |||
T6372 | Albendazole sulfoxide | Ricobendazole,Albendazole Oxide | Microtubule Associated , Parasite |
Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic. | |||
T34070 | Piperitenone oxide | Rotundifolone,Lippione,cis-Piperitenone epoxide,Piperitenone oxide, (+-)- | |
Piperitenone oxide is a major chemical constituent of the carvone pathway MS essential oil. | |||
T20946 | Bismuth oxide | Bismuth sesquioxide,Bismuth trioxide,Bismutum-oxydatum,Bismuthous oxide | |
Bismuth(III) oxide is a common starting point for bismuth chemistry. It is usually obtained as a by-product of the smelting of copper and lead ores. Bismuth trioxide is commonly used as a replacement of red lead to produ... | |||
T12213 | Netupitant metabolite Netupitant N-oxide | Netupitant N-oxide | Others |
Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite. | |||
T40706 | Heliotrine N-oxide | ||
Heliotrine N-oxide is the pyrrolizidine alkaloid (PA) N-oxide counterpart of Heliotrine. It induces the generation of pyrrolic DNA adducts, potentially initiating PA-induced liver tumors in vivo. | |||
T35882 | Rizatriptan N-oxide | ||
Rizatriptan N-oxide is a potential impurity found in commercial preparations of rizatriptan.1It is a degradation product formed under oxidative conditions. | |||
T37246 | Palonosetron N-oxide | ||
Palonosetron N-oxide is a metabolite of the serotonin (5-HT) receptor subtype 5-HT3antagonist palonosetron .1It is also a potential impurity in palonosetron preparations.2Palonosetron N-oxide is a degradation product for... | |||
T37796 | Voriconazole N-oxide | ||
Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole . It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19. | |||
T36795 | Donepezil N-oxide | ||
Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil . Donepezil N-oxide inhibits cholinesterase (ChE) activity in human erythrocytes in a concentration-dependent manner, exhibiting 4... | |||
T36681 | Sorafenib N-oxide | ||
Sorafenib N-oxide is an active metabolite of sorafenib , an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases. Sorafenib N-oxide inhibits FLT3 that contains the internal tandem duplication mutation (FLT3-ITD; Kd =... | |||
T37430 | Mirtazapine N-oxide | ||
Mirtazapine N-oxide is a metabolite of mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4 in human liver microsomes. | |||
T69828 | Melarsen oxide | ||
Melarsen oxide is a glutathione reductase inhibitor. | |||
T77790 | Phenylarsine oxide | Oxophenylarsine | |
Phenylarsine Oxide (Oxophenylarsine) is a membrane-permeable tyrosine phosphatase inhibitor with an IC50 value of 18 µM that stimulates 2-deoxyglucose transport in insulin-resistant human skeletal muscle. | |||
T25942 | Phenazine oxide | ||
Phenazine oxide is a Bactericide, Fungicide, and Wood Preservative. | |||
T33214 | Manoyl oxide | Manoyl | |
Manoyl oxide is a proposed intermediate in the biosynthesis of forskolin and other medically important labdane-type terpenoids. | |||
T27235 | Ebselen oxide | ||
Ebselen oxide is a dose-dependent inhibitor of HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9. | |||
T22739 | DMPO | 5,5-Dimethyl-1-pyrroline N-oxide | Others |
DMPO (5,5-Dimethyl-1-pyrroline N-oxide) is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin reson... | |||
T37643 | Propiverine N-oxide (hydrochloride) | ||
Propiverine N-oxide (hydrochloride) is the major metabolite of propiverine in human plasma or urine. | |||
T37432 | Erythromycin A N-oxide | ||
Erythromycin A N-oxide is a potential impurity found in commercial preparations of erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, bl... | |||
T19545 | Raloxifene N-Oxide | Others | |
Raloxifene N-Oxide is a Raloxifene oxidative degradation product. | |||
T32638 | Leontalbinine N-oxide | ||
Leontalbinine N-oxide is a lupin alkaloid from Sophora flavescen seeds. | |||
T32917 | Lucanthone N-oxide | ||
Lucanthone N-oxide is a bioactive chemical. | |||
T32756 | Limonene oxide, (-)- | FEMA No. 4656,L-1,2-Epoxylimonene | |
Limonene oxide, (-)- is a bioactive chemical. | |||
T19929 | Ranitidine-S-oxide | ||
Ranitidine-S-oxide is a metabolite of Ranitidine. It is commonly used in the treatment of peptic ulcer disease, Zollinger–Ellison syndrome,and gastroesophageal reflux disease. | |||
T19176 | Acetylseneciphylline N-oxide | Others | |
Acetylseneciphylline N-oxide is a pyrrolizine alkaloid. | |||
T10257 | Afatinib N-Oxide | Others | |
Afatinib N-Oxide is an impurity of Afatinib in oxidative degradation. Afatinib is an irreversible EGFR family inhibitor. | |||
T20775 | Ranitidine-N-oxide | ||
Ranitidine-N-oxide is a metabolite of Ranitidine. Ranitidine is a antagonist of histamine H2-receptor, it inhibits the normal and meal-stimulated secretion of stomach acid. Ranitidine is a medication decreaseing stomach ... | |||
T13203 | Trimetazidine-N-oxide | Others | |
Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long-chain inhibitor of 3-ketoyl coenzyme A thiolase (IC50: 75 nM), has anti-oxidant, anti-inflammatory, antinociceptive... | |||
T11385 | Gefitinib N-oxide | Others | |
Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib N-oxide is the N-oxide derivative of Gefitinib. | |||
T32685 | Leurosidine N'b-oxide | ||
Leurosidine N'b-oxide is a catharanthus alkaloid extracted from Madagascan periwinkle Catharanthus roseus. | |||
T20732 | Lignocaine N-oxide | ||
Lignocaine N-oxide is a metabolite of Lidocaine, which is an antiarrhythmic and anesthetic agent. | |||
T25753 | Loperamide oxide | R 58425,R58425,R-58425 | |
Loperamide oxide is a prodrug of loperamide, the effective antidiarrheal. | |||
T19800 | Fenbutatin oxide | Neostanox,Bendex,Osdaran,Vendex,Torque | |
Fenbutatin oxide is an organometallic insecticide chemical. It mainly used in agricultural practices to kill ticks and mites. | |||
T23763 | Atropine Oxide | NSC 72861,NSC72861,NSC-72861 | |
Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and ... | |||
T4604 | HC-056456 | HC 056456,3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide | Others |
HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0617 | Nicotinamide N-oxide | Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide | c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite |
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n... | |||
T2724 | Caryophyllene oxide | Others , Endogenous Metabolite | |
Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity. | |||
T41245 | Trimethylamine N-oxide | Reactive Oxygen Species , NOD-like Receptor (NLR) , TGF-beta/Smad | |
Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging e... | |||
TN7068 | Sinomenine N-oxide | Others | |
Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine. | |||
T11351 | Galanthamine N-Oxide | AChE | |
Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 μM. It acts as a significant inhibitor of substrate ac... | |||
T19433 | Monocrotaline N-Oxide | Others | |
Monocrotaline N-Oxide is a monocrotaline metabolite. | |||
T5247 | Trimethylamine N-oxide dihydrate | TMANO Dihydrate | Others , Endogenous Metabolite |
Trimethylamine N-oxide dihydrate (TMANO Dihydrate), a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. | |||
T40519 | Indicine N-oxide | (+)-Indicine N-oxide,Indicine N-oxide,NSC132319 | |
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research. | |||
TN2203 | Senecionine N-oxide | Senecionine oxide | |
Senecionine n-oxide is a major product of pyrrolizidine nucleic alkaloid biosynthesis in unusual root cultures of Trichoderma lucidum.Senecionine N-oxide (Senecionine oxide) has antitumor activity but induces hepatic sin... | |||
T2S1008 | Oxysophoridine | Sophoridine N-oxide | Apoptosis , Antioxidant |
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ... | |||
T2833 | Dehydrocostus Lactone | Epiligulyl oxide,(-)-Dehydrocostus lactone | IκB/IKK |
Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties. | |||
T2754 | Oxymatrine | Oxysophoridine,Matrine N-oxide | Influenza Virus , Autophagy , TGF-beta/Smad |
Oxymatrine (Oxysophoridine) is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis B virus.It can also inhibit iNOS expressio... | |||
T39794 | Bisabolone oxide A | ||
Bisabolone oxide A is an α-glucosidase inhibitor. | |||
T40512 | Echimidine N-oxide | ||
Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM. | |||
T2982 | Xanthone | Genicide,Xanthenone,Benzophenone oxide | Apoptosis , Others , Influenza Virus , Antibacterial , Antifungal |
Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide. | |||
TN6695 | Alpha-Pinene oxide | ||
alpha-Pinene oxide is a natural product for research related to life sciences. The catalog number is TN6695 and the CAS number is 1686-14-2. | |||
TN4396 | Koumine N-oxide | Others | |
Koumine N-oxide is a natural product from Gelsemium elegans. | |||
T13266 | Usaramine N-oxide | Others | |
Usaramine N-oxide is a flavonoid isolated from Crotalaria pallida, and possesses anti-inflammatory activities. | |||
TN2204 | Seneciphylline N-oxide | ||
Seneciphylline N-oxide is a pyrrolizidine alkaloid obtained from Emilia sonchifolia and is the dehydrogenation product of Senecionine N-oxide. | |||
TN4952 | Sarracine N-oxide | Others | |
Sarracine N-oxide is a natural product of Senecio, Asteraceae. The catalog number is TN4952 and the CAS number is 19038-27-8. Sarracine N-oxide can be used as a reference standard. | |||
T40484 | Jacobine N-oxide | ||
Jacobine N-oxide is a pyrrolizidine alkaloid compound found in thrips-resistant Senecio hybrids. | |||
TN4955 | Scandine Nb-oxide | Others | |
Scandine Nb-oxide is a natural product from Melodinus fusiformis. | |||
TN3915 | Echinatine N-oxide | Others | |
Echinatine N-oxide is a natural product for research related to life sciences. The catalog number is TN3915 and the CAS number is 20267-93-0. | |||
TN5219 | Vallesamine N-oxide | Others | |
Vallesamine N-oxide is a natural product for research related to life sciences. The catalog number is TN5219 and the CAS number is 126594-73-8. | |||
TN4335 | Isotetrandrine N-2'-oxide | Others | |
Isotetrandrine N-2'-oxide is a natural product for research related to life sciences. The catalog number is TN4335 and the CAS number is 70191-83-2. | |||
T32198 | Retrorsine N-oxide | Isatidine | |
Isatidine is a pyrrolizidine alkaoid. | |||
TN2146 | Retronecine N-oxide | Others | |
Retronecine N-oxide is a natural product | |||
TN6113 | 3β-Isodihydrocadambine 4-oxide | ||
3β-Isodihydrocadambine 4-oxide is a natural product for research related to life sciences. The catalog number is TN6113 and the CAS number is 1092371-18-0. | |||
TN4655 | Nicotine 1'-N-oxide | Others | |
Nicotine 1'-N-oxide is a natural product from tobacco smoke. | |||
TN3312 | 9-Angeloylretronecine N-oxide | Others | |
9-Angeloylretronecine N-oxide is a natural product for research related to life sciences. The catalog number is TN3312 and the CAS number is 27773-86-0. | |||
T25634 | Lasiocarpine N-oxide | 4-21-00-02054 (Beilstein Handbook Reference) | |
Lasiocarpine N-oxide is a natural compound found to be higher in many tea bags, herbal drugs and honey by mass spectrometry. | |||
TN3584 | Canthin-6-one N-oxide | Antifection | |
Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities. | |||
TN1446 | Bisabolol oxide A | Others | |
Bisabololoxide A induces apoptosis in rat thymocytes. | |||
TN6652 | 1-Methoxycarbonyl-beta-carboline-N-oxide | ||
1-Methoxycarbonyl-beta-carboline-N-oxide is a natural product for research related to life sciences. The catalog number is TN6652 and the CAS number is 74690-74-7. | |||
TN3322 | 9-Methoxycanthin-6-one-N-oxide | Others | |
9-Methoxycanthin-6-one-N-oxide shows cytotoxic activity against a panel of cell lines comprising a number of human cancer cell types. | |||
T78483 | Benzydamine N-Oxide | ||
Benzydamine N-Oxide, a metabolite of Benzydamine, serves as a biomarker for flavin-containing monooxygenase activity [1] [2]. | |||
T81273 | Rinderine N-oxide | ||
Rinderine N-oxide, a pyrrolizidine alkaloid, is present in R. graeca [1]. | |||
TQ0301 | Kuwanon A | NO Synthase | |
Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L. | |||
T6S2023 | Harpagoside | Others , COX , NO Synthase | |
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression... | |||
T6S1665 | Irisflorentin | Others , NO Synthase | |
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan... | |||
T7682 | Asymmetric dimethylarginine | Endogenous Metabolite , NO Synthase , NOD | |
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS) | |||
T2S0765 | Epibetulinic acid | NO Synthase , Prostaglandin Receptor | |
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin. | |||
TN1058 | Pelargonidin chloride | NOS , Reactive Oxygen Species , Nrf2 , NO Synthase | |
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. | |||
T3847 | Asperuloside | Asperulosid | Others , NO Synthase |
Asperuloside (Asperulosid) has anti-inflammatory activity. | |||
T5838 | L-Canavanine sulfate | NO Synthase , NOD | |
L-Canavanine sulfate is a selective inducible NO synthase inhibitor. | |||
T5S0285 | Cistanoside A | Others | |
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat... | |||
T19161 | 7α-Hydroxycholesterol | Others | |
7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation. | |||
T2791 | Pectolinarin | Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin | |
Pectolinarin is a Cirsium isolate with anti-inflammatory activity. | |||
T4808 | Agmatine sulfate | Agmatine sulfate salt | Endogenous Metabolite , NO Synthase , Imidazoline Receptor |
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy... | |||
T7597 | 6-Biopterin | L-Biopterin | Endogenous Metabolite , NO Synthase , NOD |
6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01052 | DYNLL1 Protein, Human, Recombinant (His) | Human | E. coli |
Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, an... | |||
TMPH-00052 | Superoxide dismutase [Fe] Protein, Anabaena sp., Recombinant (His & KSI) | Anabaena sp. | E. coli |
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | |||
TMPY-00382 | Thioredoxin/TRX Protein, Mouse, Recombinant | Mouse | E. coli |
Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act ... | |||
TMPY-00545 | Dermcidin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia... | |||
TMPY-04793 | IL-35 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ... | |||
TMPY-02900 | IL-17A Protein, Mouse, Recombinant | Mouse | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-02886 | IL-17A Protein, Human, Recombinant | Human | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPH-00683 | TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc) | E. coli | E. coli |
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. | |||
TMPY-03172 | Argininosuccinate lyase Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established r... | |||
TMPH-02575 | PDE5A Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-gen... | |||
TMPH-01733 | DDAH2 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. | |||
TMPH-01732 | DDAH1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. | |||
TMPH-02897 | SPINK1 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulat... | |||
TMPJ-01248 | Cytoglobin/CYGB Protein, Human, Recombinant (His) | Human | E. coli |
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be... | |||
TMPY-02250 | Thioredoxin/TRX Protein, Human, Recombinant | Human | E. coli |
Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act ... | |||
TMPH-02136 | SPSB1 Protein, Human, Recombinant (His) | Human | E. coli |
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Nega... | |||
TMPJ-00826 | TXN Protein, Human, Recombinant (His) | Human | E. coli |
Thioredoxin (TXN) is a member of the Thioredoxin family. Thioredoxin exists as a disulfide-linked homodimer and contains one Thioredoxin domain. Thioredoxin is up-regulated by ionizing radiation. Thioredoxin participates... | |||
TMPJ-01058 | ARG2 Protein, Human, Recombinant (His) | Human | E. coli |
Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not found... | |||
TMPJ-01112 | PRKG1 Protein, Human, Recombinant (His) | Human | Human Cells |
cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one pro... | |||
TMPY-06105 | IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His) | Human | HEK293 |
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ... | |||
TMPY-03879 | IL-35 Protein, Human, Recombinant | Human | HEK293 |
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ... | |||
TMPJ-00693 | EDF1 Protein, Human, Recombinant (His) | Human | E. coli |
Endothelial Differentiation-Related Factor 1 (EDF1) is a 148 amino acid transcriptional coactivator that contains 1 HTH cro/C1-type DNA-binding domain. It has been postulated that the protein functions as a bridging mole... | |||
TMPH-02526 | Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth... | |||
TMPY-02168 | Arginase 1/ARG1 Protein, Human, Recombinant (His) | Human | HEK293 |
Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxid... | |||
TMPJ-00802 | THBS1 Protein, Human, Recombinant (His) | Human | Human Cells |
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w... | |||
TMPY-04685 | Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC) | Human | HEK293 |
Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxid... | |||
TMPY-04710 | IL-17 Protein, Rhesus, Recombinant | Rhesus | Baculovirus-Insect Cells |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-03568 | IL-17A Protein, Human, Recombinant (His) | Human | Yeast |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-02640 | FAM3B Protein, Human, Recombinant (hFc) | Human | HEK293 |
Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and b... | |||
TMPY-04888 | IL-17 Protein, Rabbit, Recombinant | Rabbit | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-05342 | IL-17A Protein, Cynomolgus, Recombinant | Cynomolgus | Baculovirus-Insect Cells |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-05183 | IL-17A Protein, Human, Recombinant, Biotinylated | Human | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-04332 | IL-17A Protein, Human, Recombinant (T26A, His) | Human | Baculovirus-Insect Cells |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-04609 | IL-17 Protein, Rabbit, Recombinant (His) | Rabbit | Baculovirus-Insect Cells |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-03906 | IL-17 Protein, Canine, Recombinant | Canine | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-03931 | IL-17 Protein, Marmoset, Recombinant | Marmoset | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPH-02525 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... | |||
TMPH-02524 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... | |||
TMPY-01409 | IL-12A Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ... | |||
TMPY-04105 | IL-12A Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ... | |||
TMPY-00838 | IL-12A Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ... | |||
TMPY-04631 | CD98 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-03307 | CD98 Protein, Rat, Recombinant (His) | Rat | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-06611 | CD98 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPH-01045 | CEACAM1 Protein, Human, Recombinant | Human | E. coli |
Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi... | |||
TMPH-01044 | CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi... |
Cat No. | Product Name | ||
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L5400 | Anti-Cardiovascular Disease Compound Library | 1428 compounds | |
A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS); |