Search Result

Search Results for " nitric "

Targets

NO Synthase

222

Compounds

160

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T79981	Nitric oxide production-IN-1		NO Synthase
	Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis. It effectively suppresses NO synthesis in rat abdominal macrophages upon stimulation with lipop...		NO Synthase
TP2195	Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell		Others
	Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the pro...		Others
T7474	7-Nitroindazole		NOS
	7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.		NOS
T10107	3-Bromo-7-nitroindazole		NOS
	3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messenger NO synthesis throughout the brain and body.		NOS
T1322	Bendazol	Dibazol,Dibazole	Dopamine Receptor , NO Synthase
	Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.		Dopamine Receptor , NO Synthase
T22724	Dimaprit dihydrochloride		NOS , NO Synthase , Histamine Receptor
	Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion.		NOS , NO Synthase , Histamine Receptor
T21712	BAY 41-8543		Others , Guanylate cyclase
	BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).		Others , Guanylate cyclase
T15697	L-NMMA acetate	Tilarginine acetate,Methylarginine acetate	NOS
	L-NMMA acetate (Tilarginine acetate) is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6 µM for nNOS, eNOS, and iNOS, respectively.		NOS
T19853	Dimethoxycurcumin	Veratrylcurcuminoid	Others
	Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes.		Others
T21507	7-Ethoxyresorufin	Resorufin ethyl ether	P450 , NO Synthase
	7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.		P450 , NO Synthase
T21700	NOS-IN-1	2-Imino-4-methylpiperidine (acetate)	NOS
	NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectiv...		NOS
T2334	Avanafil	TA1790	PDE
	Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.		PDE
T7461	2,4-Diamino-6-hydroxypyrimidine	DAHP	Reactive Oxygen Species , NO Synthase
	2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis		Reactive Oxygen Species , NO Synthase
T12808	S-Nitroso-N-acetyl-DL-penicillamine	SNAP	NO Synthase
	S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .		NO Synthase
T3491	1400W dihydrochloride	1400W 2HCl,N-(3-(Aminomethyl)benzyl)acetamidine	NOS , NO Synthase
	1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).		NOS , NO Synthase
T19916	TRIM	1-(2-Trifluoromethylphenyl)imidazole	NOS
	TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.		NOS
T7206L	2-Iminobiotin hydrobromide	Guanidinobiotin	NOS , NO Synthase
	2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse i...		NOS , NO Synthase
T1479	Isosorbide dinitrate	Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate	Others , NO Synthase
	Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.		Others , NO Synthase
T3198L	PRE-084 hydrochloride		Sigma receptor
	PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).		Sigma receptor
T1102	Mifepristone	C-1073,RU486,RU 38486	Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , NO Synthase , Autophagy
	Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
T22419	S-Methylisothiourea sulfate	(S)-Methylisothiourea sulfate	NOS , NO Synthase , HSV
	S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock[1].		NOS , NO Synthase , HSV
T6888	Methylene Blue	methylthioninium chloride,CI-52015,Tetramethylthionine chloride,Basic Blue 9	Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase
	Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
T0006	Methylene Blue trihydrate	Methylthionine chloride,Basic blue 9,Methylene Blue	Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase
	Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate...
T3211	Midostaurin	N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251	Others , PKC
	PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...		Others , PKC
T6570	L-NAME hydrochloride	L-NAME HCl,N(G)-Nitro-L-arginine methyl ester,NG-Nitroarginine methyl ester hydrochloride	NOS , NO Synthase
	L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) , and eNOS (human), respectively.		NOS , NO Synthase
T0358	Aminoguanidine hydrochloride	Imino semicarbazide,Pimagedine hydrochloride,CP-12009-18 tartrate,Hydrazinecarboximidamide,Guanyl hydrazine,Pimagedine	NOS , NO Synthase
	Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.		NOS , NO Synthase
T9537	N'-Nitro-D-arginine	N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid	Others
	N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.		Others
T7206	2-Iminobiotin	2-IMINOBIOTIN HYDROBROMIDE,Guanidinobiotin	NOS , NO Synthase
	2-Iminobiotin (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat n...		NOS , NO Synthase
T31448	Diethylamine dinitric oxide adduct	DEANO
	Diethylamine dinitric oxide adduct is a nitric oxide generator.
T19032	Nitro blue tetrazolium chloride	NBT	NO Synthase
	Nitro blue tetrazolium chloride (NBT) is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 M). A well-known scavenger of superoxide anions.Nitro blue tetrazolium chloride, a subst...		NO Synthase
T33716	Norathiol	NOX 100,NOX100,NOX-100
	Norathiol(NOX-100) is nitric oxide (NO) scavenging agent that may be used to prevent hypotension during hemodialysis and septic shock.
T9442	4-Chloro-3-nitrobenzoic acid		Others
	4-Chloro-3-nitrobenzoic acid is a nitric oxide scavenger and has been used to study the effects of nitric oxide on the cardiovascular system and the effects of nitric oxide on the immune system.		Others
T28497	RA-839	RA 839,RA839	Nrf2
	RA-839 is a potent small molecule Keap1 conjugate and selective Nrf2 signalling activator, as well as an inhibitor of Keap1/Nrf2 interaction with anticancer activity.RA-839 inhibits the expression of inducible nitric oxi...		Nrf2
T11518L	GW274150		NOS
	GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endoth...		NOS
T21546	NG,NG-dimethyl-L-Arginine dihydrochloride		NO Synthase
	NG,NG-dimethyl-L-Arginine dihydrochloride is an endogenous nitric oxide synthase inhibitor. Nitric oxide (NO) that is synthesised from L-arginine contributes to the regulation of blood pressure and to host defence[1].		NO Synthase
T19480	NO-prednisolone	NCX-1015	IL Receptor
	NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo. It is a Prednisolone derivative that releases nitric oxide (NO).		IL Receptor
T9826	GDC-0214		JAK
	GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).		JAK
T39020	Carboxyebselen	Carboxyebselen,HOOC-Ebs	NOS
	Carboxyebselen (HOOC-Ebs) is an endothelial nitric oxide synthase (eNOS) inhibitor that is potent and selective.		NOS
T3147	Pyrrolidinedithiocarbamate ammonium	PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate	NF-κB
	Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.		NF-κB
T7201	Nelociguat	BAY60-4552	Guanylate cyclase
	Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.		Guanylate cyclase
T31795	FK-330	LS-192510,FR-260330,FK330,FK 330	NOS
	FK-330 (FR-260330) is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity that prevents ischemia and reperfusion injury in rat liver transplantation.		NOS
T25865	NG-Nitroarginine methyl ester	ω-Nitroarginine methyl,L-NAME	NO Synthase
	NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hypertension.		NO Synthase
T4381	Lificiguat	YC-1	Others , Guanylate cyclase , HIF
	Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).		Others , Guanylate cyclase , HIF
T9376	Nitroarginine	N'-Nitro-L-arginine	NO Synthase
	Nitroarginine (N'-Nitro-L-arginine) is a competitive inhibitor of nitric oxide synthase which causes the selective reduction of blood flow to tumor cells[1].		NO Synthase
T83625	INOS-IN-14	3-bromo-1H-indazole-7-carbonitrile	NOS
	iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.		NOS
TP2057L	Camstatin acetate		NO Synthase
	Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19.		NO Synthase
T21443	Prednicarbate	Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D	Others
	Prednicarbate (Hoe 777) is a Corticosteroid Hormone Receptor Agonist. Prednicarbate has antipruritic, anti-inflammatory, and vasoconstrictive properties. It also decreases the number of circulating lymphocytes by inhibit...		Others
T0154	Nebivolol hydrochloride	R 065824 hydrochloride,Nebivolol HCl,R-65824	Apoptosis , Adrenergic Receptor
	Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us...		Apoptosis , Adrenergic Receptor
T20684	2',7'-Dichlorofluorescein diacetate	Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA	Others
	2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the d...		Others
T0109	Molsidomine	Morsydomine,SIN-10,Corvaton	NOD
	Molsidomine (Corvaton) is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.		NOD

Compounds

Nitric oxide production-IN-1

T79981

Synonym:

Target: NO Synthase

Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

3-Bromo-7-nitroindazole

Synonym: Dibazol,Dibazole

Target: Dopamine Receptor, NO Synthase

Dimaprit dihydrochloride

T22724

Synonym:

Target: NOS, NO Synthase, Histamine Receptor

BAY 41-8543

T21712

Synonym:

Target: Others, Guanylate cyclase

L-NMMA acetate

T15697

Synonym: Tilarginine acetate,Methylarginine acetate

Target: NOS

Dimethoxycurcumin

T19853

Synonym: Veratrylcurcuminoid

Target: Others

7-Ethoxyresorufin

T21507

Synonym: Resorufin ethyl ether

Target: P450, NO Synthase

NOS-IN-1

T21700

Synonym: 2-Imino-4-methylpiperidine (acetate)

2,4-Diamino-6-hydroxypyrimidine

T7461

Synonym: DAHP

Target: Reactive Oxygen Species, NO Synthase

S-Nitroso-N-acetyl-DL-penicillamine

T12808

Synonym: SNAP

Target: NO Synthase

1400W dihydrochloride

T3491

Synonym: 1400W 2HCl,N-(3-(Aminomethyl)benzyl)acetamidine

Target: NOS, NO Synthase

TRIM

T19916

Synonym: 1-(2-Trifluoromethylphenyl)imidazole

Target: NOS

2-Iminobiotin hydrobromide

T7206L

Synonym: Guanidinobiotin

Target: NOS, NO Synthase

Isosorbide dinitrate

T1479

Synonym: Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate

Target: Others, NO Synthase

PRE-084 hydrochloride

T3198L

Synonym:

Target: Sigma receptor

Mifepristone

T1102

Synonym: C-1073,RU486,RU 38486

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, NO Synthase, Autophagy

S-Methylisothiourea sulfate

T22419

Synonym: (S)-Methylisothiourea sulfate

Target: NOS, NO Synthase, HSV

Methylene Blue

T6888

Synonym: methylthioninium chloride,CI-52015,Tetramethylthionine chloride,Basic Blue 9

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

Methylene Blue trihydrate

T0006

Synonym: Methylthionine chloride,Basic blue 9,Methylene Blue

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

Midostaurin

T3211

Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251

Target: Others, PKC

L-NAME hydrochloride

T6570

Synonym: L-NAME HCl,N(G)-Nitro-L-arginine methyl ester,NG-Nitroarginine methyl ester hydrochloride

Target: NOS, NO Synthase

Aminoguanidine hydrochloride

T0358

Synonym: Imino semicarbazide,Pimagedine hydrochloride,CP-12009-18 tartrate,Hydrazinecarboximidamide,Guanyl hydrazine,Pimagedine

Target: NOS, NO Synthase

N'-Nitro-D-arginine

T9537

Synonym: N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid

Target: Others

2-Iminobiotin

T7206

Synonym: 2-IMINOBIOTIN HYDROBROMIDE,Guanidinobiotin

Target: NOS, NO Synthase

Diethylamine dinitric oxide adduct

T31448

Synonym: DEANO

Target:

Nitro blue tetrazolium chloride

Synonym: NOX 100,NOX100,NOX-100

Target:

4-Chloro-3-nitrobenzoic acid

Synonym: RA 839,RA839

NG,NG-dimethyl-L-Arginine dihydrochloride

Synonym: Carboxyebselen,HOOC-Ebs

Target: NOS

Pyrrolidinedithiocarbamate ammonium

T3147

Synonym: PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate

Target: Guanylate cyclase

FK-330

T31795

Synonym: LS-192510,FR-260330,FK330,FK 330

Target: NOS

NG-Nitroarginine methyl ester

T25865

Synonym: ω-Nitroarginine methyl,L-NAME

Target: Others, Guanylate cyclase, HIF

Nitroarginine

T9376

Synonym: N'-Nitro-L-arginine

Target: NO Synthase

iNOS-IN-14

T83625

Synonym: 3-bromo-1H-indazole-7-carbonitrile

Synonym: Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D

Target: Others

Nebivolol hydrochloride

T0154

Synonym: R 065824 hydrochloride,Nebivolol HCl,R-65824

Target: Apoptosis, Adrenergic Receptor

2',7'-Dichlorofluorescein diacetate

T20684

Synonym: Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA

Target: Others

Molsidomine

T0109

Synonym: Morsydomine,SIN-10,Corvaton

Target: NOD

Cat No.	Product Name	Synonyms	Targets
TQ0301	Kuwanon A		NO Synthase
	Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L.		NO Synthase
T6S2023	Harpagoside		Others , COX , NO Synthase
	1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression...		Others , COX , NO Synthase
T2S0765	Epibetulinic acid		NO Synthase , Prostaglandin Receptor
	Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.		NO Synthase , Prostaglandin Receptor
T6S1665	Irisflorentin		Others , NO Synthase
	1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan...		Others , NO Synthase
T7682	Asymmetric dimethylarginine		Endogenous Metabolite , NO Synthase , NOD
	Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)		Endogenous Metabolite , NO Synthase , NOD
TN1058	Pelargonidin chloride		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
T3847	Asperuloside	Asperulosid	Others , NO Synthase
	Asperuloside (Asperulosid) has anti-inflammatory activity.		Others , NO Synthase
T5838	L-Canavanine sulfate		NO Synthase , NOD
	L-Canavanine sulfate is a selective inducible NO synthase inhibitor.		NO Synthase , NOD
T5S0285	Cistanoside A		Others
	1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat...		Others
T2791	Pectolinarin		Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
	Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T7597	6-Biopterin	L-Biopterin	Endogenous Metabolite , NO Synthase , NOD
	6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor.		Endogenous Metabolite , NO Synthase , NOD
T4808	Agmatine sulfate	Agmatine sulfate salt	Endogenous Metabolite , NO Synthase , Imidazoline Receptor
	Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy...		Endogenous Metabolite , NO Synthase , Imidazoline Receptor
TN2139	Regaloside B		NOS , COX , NO Synthase
	Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2).		NOS , COX , NO Synthase
T2980	Chondroitin sulfate	Chonsurid,Chondroitin polysulfate	MMP , Others , Endogenous Metabolite , NO Synthase
	Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition		MMP , Others , Endogenous Metabolite , NO Synthase
T2S2335	Dehydroevodiamine	DHED	Others , NF-κB , COX , PGE Synthase , NO Synthase
	Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood fl...		Others , NF-κB , COX , PGE Synthase , NO Synthase
T1310	2-Thiouracil	Thiouracil,Deracil	Thyroid hormone receptor(THR) , NO Synthase
	2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.		Thyroid hormone receptor(THR) , NO Synthase
T3S0364	L-Arginine	L-Arg,(S)-(+)-Arginine	IL Receptor , Endogenous Metabolite , NO Synthase
	1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...		IL Receptor , Endogenous Metabolite , NO Synthase
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
TN1373	α-Humulene	Alpha-caryophyllene	TNF , NOS , COX
	α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production an...		TNF , NOS , COX
T7786	Tryptanthrin		DNA gyrase
	Tryptanthrin is a natural DNA gyrase inhibitor.		DNA gyrase
T5681	ETHYL CAFFEATE	ETHYL 3,4-DIHYDROXYCINNAMATE	NF-κB , COX , PGE Synthase , NO Synthase
	Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s...		NF-κB , COX , PGE Synthase , NO Synthase
T5684	Ethyl 3,4-dihydroxybenzoate		Apoptosis , Others , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , NO Synthase , Autophagy
	Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.
T0983	Penicillamine	d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine	Antibiotic
	Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...		Antibiotic
T3918	Ginsenoside Rb3	Gypenoside IV	NF-κB , COX , NO Synthase
	Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.		NF-κB , COX , NO Synthase
T3805	Prim-O-glucosylcimifugin	Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside	TNF , COX , JAK , NO Synthase
	Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.		TNF , COX , JAK , NO Synthase
T3779	Crocin II	Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B	Caspase , COX , NO Synthase
	Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres...		Caspase , COX , NO Synthase
T3811	Ginsenoside C-K	Ginsenoside compound K,Ginsenoside K	P450 , cell cycle arrest , COX , NO Synthase
	Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.		P450 , cell cycle arrest , COX , NO Synthase
T5S0754	Isoquercetin	3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside	NF-κB , Wnt/beta-catenin , NO Synthase
	1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in ...		NF-κB , Wnt/beta-catenin , NO Synthase
T0670	L-Arginine hydrochloride	(S)-(+)-Arginine hydrochloride,L-Arginine HCl (L-Arg),L-arginine monohydrochloride	Amino Acids and Derivatives , Endogenous Metabolite , NO Synthase
	L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide.
T2758	Madecassic acid	6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose	Others , TNF , COX , NO Synthase , Interleukin
	Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.		Others , TNF , COX , NO Synthase , Interleukin
T3S0401	Piceatannol 3'-O-glucoside	Piceatannol 3-glycoside,Quzhaqigan	Arginase , NO Synthase
	Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung injury.		Arginase , NO Synthase
TN1102	Physalin L		Others , NO Synthase
	Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation.		Others , NO Synthase
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid	3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid	NOS , NO Synthase , Prostaglandin Receptor
	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells.		NOS , NO Synthase , Prostaglandin Receptor
T13686	Ergolide		NF-κB
	Ergolide, a sesquiterpene lactone extracted from the dried flowers of Inula Britannica, effectively hinders the expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in RAW 264.7 macrophages by deactivating...		NF-κB
TN1021	Secologanic acid		NO Synthase
	Secologanic acid is a plant growth inhibitor, it shows inhibition of nitric oxide production in lipopolysaccharide-activated macrophages.		NO Synthase
T2877	Mucic Acid	Galactaric acid,Saccharolactic acid,Schleimsaure,D-Glucaric acid,Tetrahydroxyadipic acid	Others , Endogenous Metabolite
	Mucic Acid (Tetrahydroxyadipic acid) is an aldaric acid obtained by nitric acid oxidation of galactose or galactose-containing compounds.		Others , Endogenous Metabolite
T5S1408	Pteryxin	(+)-Pteryxin	Others , AChE
	(+)-Pteryxin ((+)-Pteryxin) has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.		Others , AChE
T7344	SDMA	NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine	Endogenous Metabolite
	SDMA (Symmetric dimethylarginine) is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).		Endogenous Metabolite
T17056	Tetrahydrobiopterin	Sapropterin,BH4,(Rac)-Sapropterin	NOS , Endogenous Metabolite
	Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercho...		NOS , Endogenous Metabolite
T1391	4-Methylumbelliferone	Hymecromone,4-MU	Others
	4-Methylumbelliferone (Hymecromone) is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITR...		Others
TN2167	Rutaevin		Reactive Oxygen Species , NO Synthase
	Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent.		Reactive Oxygen Species , NO Synthase
T40388	Methyl 5-hydroxypyridine-2-carboxylate		Others
	Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production.		Others
T5721	Dehydroevodiamine hydrochloride		AChE
	Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.		AChE
TN1546	Dactylorhin A		NO Synthase
	Dactylorhin A, a succinate derivative ester isolated from the rhizomes of Gymnadenia conopsea, demonstrates a moderate inhibitory effect on nitric oxide (NO) production in RAW 264.7 macrophage cells.		NO Synthase
T4890	3-Nitro-L-tyrosine	3-Nitrotyrosine	Endogenous Metabolite
	3-Nitro-L-tyrosine (3-Nitrotyrosine) is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitric oxide (NO)-depend...		Endogenous Metabolite
T1716	Echinacoside		Reactive Oxygen Species , Wnt/beta-catenin
	Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilat...		Reactive Oxygen Species , Wnt/beta-catenin
TN1949	Moracin C		ROS , NO Synthase
	Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.		ROS , NO Synthase
T5309	Dimethylamine hydrochloride	N,N-Dimethylamine	Others
	Dimethylamine hydrochloride (N,N-Dimethylamine) is abundantly present in human urine. Main sources of urinary dimethylamine have been reported to include trimethylamine N-oxide, a common food component, and asymmetric d...		Others
T24417	Yakuchinone A	Yakuchinone-A	Others
	Yakuchinone A (Yakuchinone-A) is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro. Yakuchinone A inhibits ...		Others
TN1222	26-Deoxyactein	27-Deoxyactein,23-epi-26-Deoxyactein	NOS , CDK , NO Synthase
	23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can in...		NOS , CDK , NO Synthase
------------------------ More ------------------------

Natural Products

Target: Others, COX, NO Synthase

Epibetulinic acid

T2S0765

Synonym:

Target: NO Synthase, Prostaglandin Receptor

Irisflorentin

T6S1665

Synonym:

Target: Others, NO Synthase

Asymmetric dimethylarginine

T7682

Synonym:

Target: Endogenous Metabolite, NO Synthase, NOD

Pelargonidin chloride

TN1058

Synonym:

Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase

Asperuloside

T3847

Synonym: Asperulosid

Target: Others, NO Synthase

L-Canavanine sulfate

T5838

Synonym:

Target: NO Synthase, NOD

Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin

6-Biopterin

T7597

Synonym: L-Biopterin

Target: Endogenous Metabolite, NO Synthase, NOD

Agmatine sulfate

T4808

Synonym: Agmatine sulfate salt

Target: Endogenous Metabolite, NO Synthase, Imidazoline Receptor

Regaloside B

TN2139

Synonym:

Target: NOS, COX, NO Synthase

Chondroitin sulfate

T2980

Synonym: Chonsurid,Chondroitin polysulfate

Target: MMP, Others, Endogenous Metabolite, NO Synthase

Dehydroevodiamine

T2S2335

Synonym: DHED

Target: Others, NF-κB, COX, PGE Synthase, NO Synthase

2-Thiouracil

T1310

Synonym: Thiouracil,Deracil

Target: Thyroid hormone receptor(THR), NO Synthase

L-Arginine

T3S0364

Synonym: L-Arg,(S)-(+)-Arginine

Target: IL Receptor, Endogenous Metabolite, NO Synthase

anemarsaponin B

T7030

Synonym:

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

α-Humulene

TN1373

Synonym: Alpha-caryophyllene

Target: TNF, NOS, COX

Synonym: ETHYL 3,4-DIHYDROXYCINNAMATE

Target: NF-κB, COX, PGE Synthase, NO Synthase

Ethyl 3,4-dihydroxybenzoate

T5684

Synonym:

Target: Apoptosis, Others, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, NO Synthase, Autophagy

Penicillamine

T0983

Synonym: d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine

Target: Antibiotic

Ginsenoside Rb3

T3918

Synonym: Gypenoside IV

Target: NF-κB, COX, NO Synthase

Prim-O-glucosylcimifugin

T3805

Synonym: Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside

Target: TNF, COX, JAK, NO Synthase

Crocin II

T3779

Synonym: Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B

Target: Caspase, COX, NO Synthase

Ginsenoside C-K

T3811

Synonym: Ginsenoside compound K,Ginsenoside K

Target: P450, cell cycle arrest, COX, NO Synthase

Isoquercetin

T5S0754

Synonym: 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside

Target: NF-κB, Wnt/beta-catenin, NO Synthase

L-Arginine hydrochloride

T0670

Synonym: (S)-(+)-Arginine hydrochloride,L-Arginine HCl (L-Arg),L-arginine monohydrochloride

Target: Amino Acids and Derivatives, Endogenous Metabolite, NO Synthase

Madecassic acid

T2758

Synonym: 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose

Target: Others, TNF, COX, NO Synthase, Interleukin

Piceatannol 3'-O-glucoside

T3S0401

Synonym: Piceatannol 3-glycoside,Quzhaqigan

Target: Arginase, NO Synthase

Physalin L

TN1102

Synonym:

Target: Others, NO Synthase

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid

TN1109

Synonym: 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid

Target: NOS, NO Synthase, Prostaglandin Receptor

Synonym: Galactaric acid,Saccharolactic acid,Schleimsaure,D-Glucaric acid,Tetrahydroxyadipic acid

Target: Others, Endogenous Metabolite

Pteryxin

T5S1408

Synonym: (+)-Pteryxin

Target: Others, AChE

SDMA

T7344

Synonym: NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine

Target: Endogenous Metabolite

Tetrahydrobiopterin

T17056

Synonym: Sapropterin,BH4,(Rac)-Sapropterin

Target: NOS, Endogenous Metabolite

4-Methylumbelliferone

T1391

Synonym: Hymecromone,4-MU

Target: Reactive Oxygen Species, NO Synthase

Methyl 5-hydroxypyridine-2-carboxylate

T40388

Synonym:

Target: Others

Dehydroevodiamine hydrochloride

Synonym: 3-Nitrotyrosine

Target: Endogenous Metabolite

Echinacoside

T1716

Synonym:

Target: Reactive Oxygen Species, Wnt/beta-catenin

Moracin C

TN1949

Synonym:

Target: ROS, NO Synthase

Dimethylamine hydrochloride

T5309

Synonym: N,N-Dimethylamine

Target: Others

Yakuchinone A

T24417

Synonym: Yakuchinone-A

Target: Others

26-Deoxyactein

TN1222

Synonym: 27-Deoxyactein,23-epi-26-Deoxyactein

Target: NOS, CDK, NO Synthase

--------- More ---------

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-01052	DYNLL1 Protein, Human, Recombinant (His)	Human	E. coli
	Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, an...
TMPY-00382	Thioredoxin/TRX Protein, Mouse, Recombinant	Mouse	E. coli
	Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act ...
TMPY-00545	Dermcidin Protein, Human, Recombinant (hFc)	Human	HEK293
	Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia...
TMPY-04793	IL-35 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPY-02900	IL-17A Protein, Mouse, Recombinant	Mouse	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-02886	IL-17A Protein, Human, Recombinant	Human	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-01938	CD98 Protein, Human, Recombinant (His)	Human	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-02358	CD98 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-03172	Argininosuccinate lyase Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established r...
TMPH-02575	PDE5A Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-gen...
TMPH-01733	DDAH2 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
TMPH-01732	DDAH1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
TMPH-02161	Synapsin-1 Protein, Human, Recombinant (GST)	Human	E. coli
	Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPH-02526	Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...
TMPH-02136	SPSB1 Protein, Human, Recombinant (His)	Human	E. coli
	Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Nega...
TMPY-02250	Thioredoxin/TRX Protein, Human, Recombinant	Human	E. coli
	Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act ...
TMPJ-00826	TXN Protein, Human, Recombinant (His)	Human	E. coli
	Thioredoxin (TXN) is a member of the Thioredoxin family. Thioredoxin exists as a disulfide-linked homodimer and contains one Thioredoxin domain. Thioredoxin is up-regulated by ionizing radiation. Thioredoxin participates...
TMPJ-01058	ARG2 Protein, Human, Recombinant (His)	Human	E. coli
	Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not found...
TMPJ-01112	PRKG1 Protein, Human, Recombinant (His)	Human	Human Cells
	cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one pro...
TMPJ-00693	EDF1 Protein, Human, Recombinant (His)	Human	E. coli
	Endothelial Differentiation-Related Factor 1 (EDF1) is a 148 amino acid transcriptional coactivator that contains 1 HTH cro/C1-type DNA-binding domain. It has been postulated that the protein functions as a bridging mole...
TMPY-06105	IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPY-03879	IL-35 Protein, Human, Recombinant	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPY-04685	Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC)	Human	HEK293
	Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxid...
TMPJ-00802	THBS1 Protein, Human, Recombinant (His)	Human	Human Cells
	Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w...
TMPY-02168	Arginase 1/ARG1 Protein, Human, Recombinant (His)	Human	HEK293
	Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxid...
TMPY-05183	IL-17A Protein, Human, Recombinant, Biotinylated	Human	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-04332	IL-17A Protein, Human, Recombinant (T26A, His)	Human	Baculovirus-Insect Cells
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-04609	IL-17 Protein, Rabbit, Recombinant (His)	Rabbit	Baculovirus-Insect Cells
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-03906	IL-17 Protein, Canine, Recombinant	Canine	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-03931	IL-17 Protein, Marmoset, Recombinant	Marmoset	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-04710	IL-17 Protein, Rhesus, Recombinant	Rhesus	Baculovirus-Insect Cells
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-03568	IL-17A Protein, Human, Recombinant (His)	Human	Yeast
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-02640	FAM3B Protein, Human, Recombinant (hFc)	Human	HEK293
	Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and b...
TMPY-04888	IL-17 Protein, Rabbit, Recombinant	Rabbit	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-05342	IL-17A Protein, Cynomolgus, Recombinant	Cynomolgus	Baculovirus-Insect Cells
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPH-02524	Arginase-1/ARG1 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ...
TMPH-02525	Arginase-1/ARG1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ...
TMPH-01268	SIAH1 Protein, Human, Recombinant (GST)	Human	E. coli
	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester...
TMPY-01409	IL-12A Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ...
TMPY-04105	IL-12A Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ...
TMPY-00838	IL-12A Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ...
TMPY-06611	CD98 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-04631	CD98 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-03307	CD98 Protein, Rat, Recombinant (His)	Rat	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPH-01045	CEACAM1 Protein, Human, Recombinant	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPH-01044	CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...

DYNLL1 Protein, Human, Recombinant (His)

TMPJ-01052

Species: Human

Expression System: E. coli

Thioredoxin/TRX Protein, Mouse, Recombinant

TMPY-00382

Species: Mouse

Expression System: E. coli

Dermcidin Protein, Human, Recombinant (hFc)

TMPY-00545

Species: Human

Expression System: HEK293

IL-35 Protein, Human, Recombinant (Flag & His)

TMPY-04793

Species: Human

Expression System: HEK293

IL-17A Protein, Mouse, Recombinant

TMPY-02900

Species: Mouse

Expression System: E. coli

IL-17A Protein, Human, Recombinant

TMPY-02886

Species: Human

Expression System: E. coli

CD98 Protein, Human, Recombinant (His)

TMPY-01938

Species: Human

Expression System: HEK293

CD98 Protein, Mouse, Recombinant (His)

TMPY-02358

Species: Mouse

Expression System: HEK293

Argininosuccinate lyase Protein, Human, Recombinant (His & GST)

TMPY-03172

Species: Human

Expression System: Baculovirus-Insect Cells

PDE5A Protein, Mouse, Recombinant (His & Myc)

TMPH-02575

Species: Mouse

Expression System: E. coli

DDAH2 Protein, Human, Recombinant (GST & His)

TMPH-01733

Species: Human

Expression System: E. coli

DDAH1 Protein, Human, Recombinant (His & Myc)

TMPH-01732

Species: Human

Expression System: E. coli

Synapsin-1 Protein, Human, Recombinant (GST)

TMPH-02161

Species: Human

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02526

Species: Mouse

Expression System: E. coli

SPSB1 Protein, Human, Recombinant (His)

TMPH-02136

Species: Human

Expression System: E. coli

Thioredoxin/TRX Protein, Human, Recombinant

TMPY-02250

Species: Human

Expression System: E. coli

TXN Protein, Human, Recombinant (His)

TMPJ-00826

Species: Human

Expression System: E. coli

ARG2 Protein, Human, Recombinant (His)

TMPJ-01058

Species: Human

Expression System: E. coli

PRKG1 Protein, Human, Recombinant (His)

TMPJ-01112

Species: Human

Expression System: Human Cells

EDF1 Protein, Human, Recombinant (His)

TMPJ-00693

Species: Human

Expression System: E. coli

IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)

TMPY-06105

Species: Human

Expression System: HEK293

IL-35 Protein, Human, Recombinant

TMPY-03879

Species: Human

Expression System: HEK293

Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC)

TMPY-04685

Species: Human

Expression System: HEK293

THBS1 Protein, Human, Recombinant (His)

TMPJ-00802

Species: Human

Expression System: Human Cells

Arginase 1/ARG1 Protein, Human, Recombinant (His)

TMPY-02168

Species: Human

Expression System: HEK293

IL-17A Protein, Human, Recombinant, Biotinylated

TMPY-05183

Species: Human

Expression System: E. coli

IL-17A Protein, Human, Recombinant (T26A, His)

TMPY-04332

Species: Human

Expression System: Baculovirus-Insect Cells

IL-17 Protein, Rabbit, Recombinant (His)

TMPY-04609

Species: Rabbit

Expression System: Baculovirus-Insect Cells

IL-17 Protein, Canine, Recombinant

TMPY-03906

Species: Canine

Expression System: E. coli

IL-17 Protein, Marmoset, Recombinant

TMPY-03931

Species: Marmoset

Expression System: E. coli

IL-17 Protein, Rhesus, Recombinant

TMPY-04710

Species: Rhesus

Expression System: Baculovirus-Insect Cells

IL-17A Protein, Human, Recombinant (His)

TMPY-03568

Species: Human

Expression System: Yeast

FAM3B Protein, Human, Recombinant (hFc)

TMPY-02640

Species: Human

Expression System: HEK293

IL-17 Protein, Rabbit, Recombinant

TMPY-04888

Species: Rabbit

Expression System: E. coli

IL-17A Protein, Cynomolgus, Recombinant

TMPY-05342

Species: Cynomolgus

Expression System: Baculovirus-Insect Cells

Arginase-1/ARG1 Protein, Mouse, Recombinant (His)

TMPH-02524

Species: Mouse

Expression System: Yeast

Arginase-1/ARG1 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02525

Species: Mouse

Expression System: E. coli

SIAH1 Protein, Human, Recombinant (GST)

TMPH-01268

Species: Human

Expression System: E. coli

IL-12A Protein, Human, Recombinant (His)

TMPY-01409

Species: Human

Expression System: HEK293

IL-12A Protein, Rhesus, Recombinant (hFc)

TMPY-04105

Species: Rhesus

Expression System: HEK293

IL-12A Protein, Human, Recombinant (hFc)

TMPY-00838

Species: Human

Expression System: HEK293

CD98 Protein, Human, Recombinant (His), Biotinylated

TMPY-06611

Species: Human

Expression System: HEK293

CD98 Protein, Rat, Recombinant (hFc)

TMPY-04631

Species: Rat

Expression System: HEK293

CD98 Protein, Rat, Recombinant (His)

TMPY-03307

Species: Rat

Expression System: HEK293

CEACAM1 Protein, Human, Recombinant

TMPH-01045

Species: Human

Expression System: E. coli

CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01044

Species: Human

Expression System: E. coli

Cat No.	Product Name
L5400	Anti-Cardiovascular Disease Compound Library		1428 compounds
	A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);

Libraries

Anti-Cardiovascular Disease Compound Library

L5400

Compounds: 1428