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C25-140

C25-140
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.
Catalog No. T7889Cas No. 1358099-18-9
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Purity:98.81%
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C25-140

Catalog No. T7889Cas No. 1358099-18-9
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$68In Stock
5 mg$147In Stock
10 mg$198In Stock
25 mg$413In Stock
50 mg$679In Stock
100 mg$953In Stock
1 mL x 10 mM (in DMSO)$148In Stock
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Product Introduction

Bioactivity
Description
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.
In vitro
C25-140 inhibits the interaction between TRAF6 and Ubc13 in a dose-dependent manner. At concentrations of 10-30 μM over 2 hours, it effectively reduces TRAF6-mediated ubiquitin chain formation.
Cell Research
Cell Line:TRAF6WT . Concentration:10 μM, 20 μM, 30 μM . Incubation Time:2 hours
Chemical Properties
Molecular Weight457.57
FormulaC26H31N7O
Cas No.1358099-18-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 62.5 mg/mL (136.59 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1855 mL10.9273 mL21.8546 mL109.2729 mL
5 mM0.4371 mL2.1855 mL4.3709 mL21.8546 mL
10 mM0.2185 mL1.0927 mL2.1855 mL10.9273 mL
20 mM0.1093 mL0.5464 mL1.0927 mL5.4636 mL
50 mM0.0437 mL0.2185 mL0.4371 mL2.1855 mL
100 mM0.0219 mL0.1093 mL0.2185 mL1.0927 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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