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CBS1117

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Catalog No. T8793Cas No. 959245-08-0

CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1). It interferes with the hemagglutinin (HA)-mediated fusion process.

CBS1117

CBS1117

🥰Excellent
Purity: 99.80%
Catalog No. T8793Cas No. 959245-08-0
CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1). It interferes with the hemagglutinin (HA)-mediated fusion process.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
2 mg$68In Stock
5 mg$113In Stock
10 mg$198In Stock
25 mg$369In Stock
50 mg$539In Stock
100 mg$773In Stock
1 mL x 10 mM (in DMSO)$125In Stock
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Purity:99.80%
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Product Introduction

Bioactivity
Description
CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1). It interferes with the hemagglutinin (HA)-mediated fusion process.
Targets&IC50
H1N1:70 nM (IC50)
In vitro
CBS1117 which has a 50% inhibitory concentration of 70 nM and a selectivity index of ~4000 against A/Puerto Rico/8/34 (H1N1) infection in human lung epithelial cell line (A549).
Chemical Properties
Molecular Weight315.24
FormulaC15H20Cl2N2O
Cas No.959245-08-0
SmilesCC(C)N1CCC(CC1)NC(=O)c1c(Cl)cccc1Cl
Relative Density.1.24 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 13 mg/mL (41.24 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1722 mL15.8609 mL31.7219 mL158.6093 mL
5 mM0.6344 mL3.1722 mL6.3444 mL31.7219 mL
10 mM0.3172 mL1.5861 mL3.1722 mL15.8609 mL
20 mM0.1586 mL0.7930 mL1.5861 mL7.9305 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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