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Caroverine hydrochloride

Catalog No. T9133Cas No. 55750-05-5
Alias Caroverine HCL

Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action, and can be used for the research of inner ear tinnitus.

Caroverine hydrochloride

Caroverine hydrochloride

Purity: 98.75%
Catalog No. T9133Alias Caroverine HCLCas No. 55750-05-5
Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action, and can be used for the research of inner ear tinnitus.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$64In Stock
25 mg$133In Stock
50 mg$228In Stock
100 mg$397In Stock
200 mg$582In Stock
500 mg$913In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:98.75%
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Product Introduction

Bioactivity
Description
Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action, and can be used for the research of inner ear tinnitus.
In vivo
Caroverine (1 μM; pretreated for 10 min) inhibits the pressor response to KCl (80 mM) and noradrenaline (1 μM) in the rat hindquarter preparation. Caroverine markedly suppresses the contraction caused by KCl (40 mM) in the rat isolated aorta[1].Caroverine (1.44 mg/rat; s.c; 1.0 mL/h for 72 h) attenuates impulse noise-induced hearing loss in the rat[2]
AliasCaroverine HCL
Chemical Properties
Molecular Weight401.9
FormulaC22H28ClN3O2
Cas No.55750-05-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (248.80 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4882 mL12.4409 mL24.8818 mL124.4091 mL
5 mM0.4976 mL2.4882 mL4.9764 mL24.8818 mL
10 mM0.2488 mL1.2441 mL2.4882 mL12.4409 mL
20 mM0.1244 mL0.6220 mL1.2441 mL6.2205 mL
50 mM0.0498 mL0.2488 mL0.4976 mL2.4882 mL
100 mM0.0249 mL0.1244 mL0.2488 mL1.2441 mL

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