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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $47 | In Stock | |
10 mg | $80 | In Stock | |
25 mg | $163 | In Stock | |
50 mg | $247 | In Stock | |
1 mL x 10 mM (in DMSO) | $52 | In Stock |
Description | DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delayed rectifier potassium currents. |
In vitro | DPI 201-106(0.1 - 3 μM) produces concentration-dependent positive inotropic effects in guinea-pig and rat left atria, kitten, rabbit and guinea-pig papillary muscles and Langendorff perfused hearts of rabbits[2]. DPI 201-106 increases the Ca2+ sensitivity(EC50 = 0.2 nM) of skinned fibres from porcine trabecula septomarginalis[2]. |
In vivo | DPI 201-106(0.2 mg/kg i.v) administration increased left ventricular dP/dtmax in anesthetized dogs[3]. |
Alias | DPI-201-106 |
Molecular Weight | 466.57 |
Formula | C29H30N4O2 |
Cas No. | 97730-95-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 250 mg/mL (535.83 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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