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Digeranyl bisphosphonate

TargetMol
Catalog No. T12452Cas No. 878143-03-4
Alias DGBP

Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that impedes the geranyl pyrophosphorylation of Rac1 and induces autophagy without causing apoptosis.

Digeranyl bisphosphonate

Digeranyl bisphosphonate

TargetMol
Purity: 98.5%
Catalog No. T12452Alias DGBPCas No. 878143-03-4
Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that impedes the geranyl pyrophosphorylation of Rac1 and induces autophagy without causing apoptosis.
Pack SizePriceAvailabilityQuantity
1 mg$263In Stock
5 mg$529In Stock
10 mg$848In Stock
25 mg$1,520In Stock
50 mg$1,980In Stock
100 mg$2,500In Stock
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Purity:98.5%
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Product Introduction

Bioactivity
Description
Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that impedes the geranyl pyrophosphorylation of Rac1 and induces autophagy without causing apoptosis.
AliasDGBP
Chemical Properties
Molecular Weight536.4
FormulaC21H34Na4O6P2
Cas No.878143-03-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: <0.5 mg/mL (Insoluble)
Ethanol: <0.5 mg/mL (Insoluble)
H2O: 1.67 mg/mL (3.11 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.8643 mL9.3214 mL18.6428 mL93.2140 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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