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GSK2981278

Catalog No. T4050 CAS 1474110-21-8

Synonyms: ROR gama modulator 1

Purity 99.78% Datasheet MSDS

GSK2981278 is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).

GSK2981278, CAS 1474110-21-8

Pack Size	Availability	Price/USD
1 mg	In stock	70.00
5 mg	In stock	110.00
10 mg	In stock	160.00
25 mg	In stock	288.00
50 mg	In stock	490.00
100 mg	In stock	770.00
1 mL * 10 mM (in DMSO)	In stock	110.00

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Purity 99.52%

HNMR HPLC COA Datasheet MSDS

Purity 99.78%

HNMR HPLC COA Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	GSK2981278 is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).
Targets&IC50	RORγ,

Synonyms	ROR gama modulator 1
Purity	99.52%
Molecular Weight	461.61
Formula	C25H35NO5S
CAS No.	1474110-21-8

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Birault Veronique, et al. Preparation of tetrahydropyranylmethoxy benzenesulfonamide compounds as RORγ modulators useful in therapy of various diseases. From PCT Int. Appl. (2015), WO 2015061515 A1 20150430. 2. Birault Veronique, et al. Preparation of tertiary N-arylbenzenesulfonamides as RORγ modulators useful in treatment of inflammatory, metabolic, and autoimmune diseases. From PCT Int. Appl. (2013), WO 2013160418 A1 20131031. 3. Smith SH, et al. Development of a Topical Treatment for Psoriasis Targeting RORγ: From Bench to Skin. PLoS One. 2016 Feb 12;11(2):e0147979.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Anti-Metabolism Disease Compound Library

Related Products

Related compounds with same targets

TAK-828F Xylan Vimirogant AZD-0284 RORγt Inverse agonist 8 A-9758 S18-000003 FM26

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.