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HM-30181 mesylate monohydrate

Catalog No. T9173Cas No. 2097125-58-9

HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability of P-gp substrate drugs.

HM-30181 mesylate monohydrate

HM-30181 mesylate monohydrate

Purity: 99.37%
Catalog No. T9173Cas No. 2097125-58-9
HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability of P-gp substrate drugs.
Pack SizePriceAvailabilityQuantity
1 mg$63In Stock
2 mg$90In Stock
5 mg$128In Stock
10 mg$206In Stock
25 mg$343In Stock
50 mg$492In Stock
100 mg$715In Stock
200 mg$928In Stock
500 mg$1,390In Stock
1 mL x 10 mM (in DMSO)$197In Stock
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Purity:99.37%
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Product Introduction

Bioactivity
Description
HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability of P-gp substrate drugs.
Chemical Properties
Molecular Weight802.85
FormulaC39H42N6O11S
Cas No.2097125-58-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/ml (70.08 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2456 mL6.2278 mL12.4556 mL62.2781 mL
5 mM0.2491 mL1.2456 mL2.4911 mL12.4556 mL
10 mM0.1246 mL0.6228 mL1.2456 mL6.2278 mL
20 mM0.0623 mL0.3114 mL0.6228 mL3.1139 mL
50 mM0.0249 mL0.1246 mL0.2491 mL1.2456 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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