Powder: -20°C for 3 years | In solvent: -80°C for 1 year
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 65.00 | |
10 mg | In stock | $ 94.00 | |
25 mg | In stock | $ 157.00 | |
50 mg | In stock | $ 233.00 | |
100 mg | In stock | $ 347.00 | |
500 mg | In stock | $ 819.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 71.00 |
Description | J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy. |
Targets&IC50 | neuroprotective:60-115 nM(EC50) |
Synonyms | J147 |
Molecular Weight | 350.33 |
Formula | C18H17F3N2O2 |
CAS No. | 1146963-51-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 35 mg/mL(100 mM)
You can also refer to dose conversion for different animals. More
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J-147 1146963-51-0 Chromatin/Epigenetic GPCR/G Protein Neuroscience Dopamine Receptor Epigenetic Reader Domain Monoamine Oxidase oxidase dopamine brain disease MAO B Inhibitor SLC6A3 DAT J 147 blood neuroprotective inhibit MAO transporte monoamine Dopamine Transporter Alzheimer BBB barrier J147 inhibitor