Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 33.00 | |
5 mg | In stock | $ 52.00 | |
10 mg | In stock | $ 89.00 | |
25 mg | In stock | $ 165.00 | |
50 mg | In stock | $ 289.00 | |
100 mg | In stock | $ 428.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 58.00 |
Description | K 02288 is a novel small molecule inhibitor of ALK1/2/3/6. |
Targets&IC50 | ALK6:6.4 nM, ALK1:1.8 nM, ALK3:34.4 nM, ALK2:1.1 nM |
In vitro | In zebrafish embryos, K02288 induces dorsal phenotypes in a dose-dependent manner without affecting the formation of intersegmental vessels (ISV). |
In vivo | K02288 dose-dependently inhibits Smad1/5/8 phosphorylation induced by BMP4 and BMP6 in C2C12 cells without affecting TGF-β-BMP signaling. |
Synonyms | K 02288 |
Molecular Weight | 352.38 |
Formula | C20H20N2O4 |
CAS No. | 1431985-92-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 3.5 mg/mL (10 mM)), Heating is recommended.
DMSO: 35.2 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
K02288 1431985-92-0 Angiogenesis Stem Cells Tyrosine Kinase/Adaptors ALK TGF-beta/Smad K-02288 Inhibitor TGF-β Receptor inhibit Transforming growth factor beta receptors K 02288 inhibitor