Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 135.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 753.00 | |
50 mg | In stock | $ 1,060.00 | |
100 mg | In stock | $ 1,430.00 | |
500 mg | In stock | $ 2,860.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 317.00 |
Description | ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]. |
Targets&IC50 | T. brucei PFK:0.37 μM, T. cruzi PFK:0.13 μM |
In vitro | ML251 produces modest dose-dependent toxicity[1]. |
Cell Research | The cell cytotoxicity assay of ML251 (0~33.3 μg/mL) in T. brucei cell shows dose-dependent reduction of cell viability[1]. |
Molecular Weight | 426.27 |
Formula | C17H13Cl2N3O4S |
CAS No. | 1486482-16-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 249 mg/mL (584.13 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML251 1486482-16-9 Metabolism Microbiology/Virology Glucokinase Parasite cruzi inhibit ML 251 brucei MRC-5 Inhibitor nanomolar ML-251 inhibitor