Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
2 mg | In stock | $ 74.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 448.00 | |
50 mg | In stock | $ 658.00 | |
100 mg | In stock | $ 938.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 133.00 |
Description | ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions. |
Targets&IC50 | PvdQ acylase:20 nM (IC50) |
Molecular Weight | 280.22 |
Formula | C14H8F4N2 |
CAS No. | 1610516-67-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (214.11 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML318 1610516-67-0 Microbiology/Virology Others Antibiotic acyl-binding pyoverdine production PAO1 ML-318 Inhibitor iron P.aeruginosa PvdQ acylase site ML 318 inhibit inhibitor