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NU2058

Catalog No. T3186Cas No. 161058-83-9
Alias O6-(Cyclohexylmethyl)guanine, O(6)-Cyclohexylmethylguanine

NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.

NU2058

NU2058

Purity: 99.95%
Catalog No. T3186Alias O6-(Cyclohexylmethyl)guanine, O(6)-CyclohexylmethylguanineCas No. 161058-83-9
NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.
Pack SizePriceAvailabilityQuantity
5 mg$29In Stock
10 mg$48In Stock
25 mg$82In Stock
50 mg$127In Stock
100 mg$197In Stock
200 mg$292In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.95%
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Product Introduction

Bioactivity
Description
NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.
Targets&IC50
CDK1:26 μM, CDK2:17 μM
AliasO6-(Cyclohexylmethyl)guanine, O(6)-Cyclohexylmethylguanine
Chemical Properties
Molecular Weight247.3
FormulaC12H17N5O
Cas No.161058-83-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (242.62 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0437 mL20.2184 mL40.4367 mL202.1836 mL
5 mM0.8087 mL4.0437 mL8.0873 mL40.4367 mL
10 mM0.4044 mL2.0218 mL4.0437 mL20.2184 mL
20 mM0.2022 mL1.0109 mL2.0218 mL10.1092 mL
50 mM0.0809 mL0.4044 mL0.8087 mL4.0437 mL
100 mM0.0404 mL0.2022 mL0.4044 mL2.0218 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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