Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism. The IC50 values of perhexiline maleate against rat heart and liver CPT 1 were 77 and 148 μM, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 82.00 | |
10 mg | In stock | $ 124.00 | |
25 mg | In stock | $ 224.00 | |
50 mg | In stock | $ 332.00 | |
100 mg | In stock | $ 497.00 | |
200 mg | In stock | $ 678.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 97.00 |
Description | Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism. The IC50 values of perhexiline maleate against rat heart and liver CPT 1 were 77 and 148 μM, respectively. |
Targets&IC50 | Rat liver CPT 1:148 μM (IC50), Rat heart CPT 1:77 μM (IC50) |
In vitro | Perhexiline treatment increases the susceptibility of NB cells to antiblastic treatments. Co-administration of Perhexiline maleate potentiates the efficacy of cisplatin to reduce the in vitro clonogenic potential of NB cells[2]. |
In vivo | The co-administration of Perhexiline and cisplatin yields a clear enhancement of antitumor effects, resulting in a significantly improved progression-free survival as compared with mice treated with DMSO. |
Molecular Weight | 393.56 |
Formula | C23H39NO4 |
CAS No. | 6724-53-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (69.87 mM)
You can also refer to dose conversion for different animals. More
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Perhexiline maleate 6724-53-4 Metabolism Others Mitochondrial Metabolism inhibit Perhexiline Perhexiline Maleate Inhibitor inhibitor