Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 38.00 | |
2 mg | In stock | $ 53.00 | |
5 mg | In stock | $ 89.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 322.00 | |
50 mg | In stock | $ 513.00 | |
100 mg | In stock | $ 747.00 |
Description | RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor. |
In vitro | RO8191 strongly suppresses HCV replicon activity at 72 h in a dose-dependent manner. RO8191 reduces levels of the proteins HCV NS3 and NS4A, which are localized mainly in the perinuclear region of the replicon cells[1]. |
In vivo | RO8191 significantly induces antiviral genes Oas1b, Mx1, and Pkr in the livers of six-week-old C57BL/6J mice[1]. |
Synonyms | RO4948191, CDM-3008 |
Molecular Weight | 373.21 |
Formula | C14H5F6N5O |
CAS No. | 691868-88-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3 mg/mL (8.04 mM), Sonification and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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RO8191 691868-88-9 Angiogenesis Chromatin/Epigenetic Immunology/Inflammation JAK/STAT signaling Microbiology/Virology Proteases/Proteasome Stem Cells STAT IFNAR JAK HCV Protease HBV HCV Inhibitor Hepatitis C virus Interferon-alpha/beta receptor RO-8191 Janus kinase EMCV Tyk2 interferon RO 8191 orally RO4948191 ISGs cccDNA IFNAR1 RO-4948191 inhibit JAK1 CDM-3008 CDM 3008 Hepatitis B virus IFNAR2 imidazonaphthyridine Interferon-α/β receptor RO 4948191 replicon CDM3008 inhibitor