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Ro 46-2005

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Catalog No. T3194Cas No. 150725-87-4

Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM).

Ro 46-2005

Ro 46-2005

🥰Excellent
Purity: 98.8%
Catalog No. T3194Cas No. 150725-87-4
Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM).
Pack SizePriceAvailabilityQuantity
5 mg$38In Stock
10 mg$73In Stock
25 mg$133In Stock
50 mg$223In Stock
100 mg$319In Stock
200 mg$461In Stock
1 mL x 10 mM (in DMSO)$42In Stock
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Purity:98.8%
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Product Introduction

Bioactivity
Description
Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM).
Targets&IC50
ETA receptor:220 nM
Chemical Properties
Molecular Weight473.54
FormulaC23H27N3O6S
Cas No.150725-87-4
SmilesCOc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCO)c1
Relative Density.1.299 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (105.59 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1118 mL10.5588 mL21.1175 mL105.5877 mL
5 mM0.4224 mL2.1118 mL4.2235 mL21.1175 mL
10 mM0.2112 mL1.0559 mL2.1118 mL10.5588 mL
20 mM0.1056 mL0.5279 mL1.0559 mL5.2794 mL
50 mM0.0422 mL0.2112 mL0.4224 mL2.1118 mL
100 mM0.0211 mL0.1056 mL0.2112 mL1.0559 mL

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