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SB 242235

🥰Excellent
Catalog No. T4078Cas No. 193746-75-7
Alias SB-242235, SB242235

SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.

SB 242235

SB 242235

🥰Excellent
Purity: 99.68%
Catalog No. T4078Alias SB-242235, SB242235Cas No. 193746-75-7
SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.
Pack SizePriceAvailabilityQuantity
2 mg$40In Stock
5 mg$67In Stock
10 mg$118In Stock
25 mg$249In Stock
50 mg$378In Stock
100 mg$568In Stock
1 mL x 10 mM (in DMSO)$75In Stock
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Purity:99.68%
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Product Introduction

Bioactivity
Description
SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.
Targets&IC50
p38 MAP kinase:1.0 μM
AliasSB-242235, SB242235
Chemical Properties
Molecular Weight353.39
FormulaC19H20FN5O
Cas No.193746-75-7
SmilesCOc1nccc(n1)-c1c(ncn1C1CCNCC1)-c1ccc(F)cc1
Relative Density.1.34 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (169.78 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8297 mL14.1487 mL28.2973 mL141.4867 mL
5 mM0.5659 mL2.8297 mL5.6595 mL28.2973 mL
10 mM0.2830 mL1.4149 mL2.8297 mL14.1487 mL
20 mM0.1415 mL0.7074 mL1.4149 mL7.0743 mL
50 mM0.0566 mL0.2830 mL0.5659 mL2.8297 mL
100 mM0.0283 mL0.1415 mL0.2830 mL1.4149 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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