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Salidroside
Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
Catalog No. T2717Cas No. 10338-51-9
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Purity:99.25%
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Salidroside
Catalog No. T2717Cas No. 10338-51-9
Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $52 | In Stock | |
| 10 mg | $85 | In Stock | |
| 25 mg | $142 | In Stock | |
| 50 mg | $208 | In Stock | |
| 100 mg | $313 | In Stock | |
| 500 mg | $748 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $64 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor. |
| In vitro | Salidroside, at dosages of 20, 50, and 100 mg/kg, protects liver tissue from oxidative stress induced by D-galactosamine and LPS (lipopolysaccharide). |
| In vivo | Salidroside induces cell cycle arrest at the G1 and G2 phases in various cancer cell lines, while concurrently decreasing levels of CDK4, cyclin D1, cyclin B1, and Cdc2, and upregulating p27(Kip1) and p21(Cip1). Its concentration and time-dependent properties inhibit the growth of diverse human cancer cell lines. Salidroside activates the PI3K/Akt pathway, offering protection against MPP(+)-induced apoptosis in PC12 cells, presenting a potential treatment for Parkinson's Disease (PD). Additionally, by activating the ERK1/2 pathway and inhibiting caspase-3 activation, salidroside reduces cell viability loss and apoptotic cell death in H2O2-stimulated, NGF-differentiated PC12 cells. |
| Alias | Rhodioloside |
| Molecular Weight | 300.3 |
| Formula | C14H20O7 |
| Cas No. | 10338-51-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (183.15 mM)  Ethanol: 4 mg/mL (13.32 mM) H2O: 55 mg/mL (183.2 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO/H2O
DMSO/H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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