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Salidroside

Salidroside
Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
Catalog No. T2717Cas No. 10338-51-9
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Purity:99.25%
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Salidroside

Catalog No. T2717Cas No. 10338-51-9
Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$52In Stock
10 mg$85In Stock
25 mg$142In Stock
50 mg$208In Stock
100 mg$313In Stock
500 mg$748In Stock
1 mL x 10 mM (in DMSO)$64In Stock
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Product Introduction

Bioactivity
Description
Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
In vitro
Salidroside, at dosages of 20, 50, and 100 mg/kg, protects liver tissue from oxidative stress induced by D-galactosamine and LPS (lipopolysaccharide).
In vivo
Salidroside induces cell cycle arrest at the G1 and G2 phases in various cancer cell lines, while concurrently decreasing levels of CDK4, cyclin D1, cyclin B1, and Cdc2, and upregulating p27(Kip1) and p21(Cip1). Its concentration and time-dependent properties inhibit the growth of diverse human cancer cell lines. Salidroside activates the PI3K/Akt pathway, offering protection against MPP(+)-induced apoptosis in PC12 cells, presenting a potential treatment for Parkinson's Disease (PD). Additionally, by activating the ERK1/2 pathway and inhibiting caspase-3 activation, salidroside reduces cell viability loss and apoptotic cell death in H2O2-stimulated, NGF-differentiated PC12 cells.
AliasRhodioloside
Chemical Properties
Molecular Weight300.3
FormulaC14H20O7
Cas No.10338-51-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (183.15 mM)
Ethanol: 4 mg/mL (13.32 mM)
H2O: 55 mg/mL (183.2 mM)
Solution Preparation Table
Ethanol/DMSO/H2O
1mg5mg10mg50mg
1 mM3.3300 mL16.6500 mL33.3000 mL166.5002 mL
5 mM0.6660 mL3.3300 mL6.6600 mL33.3000 mL
10 mM0.3330 mL1.6650 mL3.3300 mL16.6500 mL
DMSO/H2O
1mg5mg10mg50mg
20 mM0.1665 mL0.8325 mL1.6650 mL8.3250 mL
50 mM0.0666 mL0.3330 mL0.6660 mL3.3300 mL
100 mM0.0333 mL0.1665 mL0.3330 mL1.6650 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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