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Sovilnesib

Catalog No. T39994Cas No. 2410796-79-9
Alias AMG650

Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.

Sovilnesib

Sovilnesib

Purity: 98.59%
Catalog No. T39994Alias AMG650Cas No. 2410796-79-9
Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.
Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$247In Stock
10 mg$396In Stock
25 mg$663In Stock
50 mg$945In Stock
100 mg$1,280In Stock
1 mL x 10 mM (in DMSO)$272In Stock
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Purity:98.59%
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Product Introduction

Bioactivity
Description
Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.
In vitro
Sovilnesib is an inhibitor of the kinesin-like protein KIF18A[1].
AliasAMG650
Chemical Properties
Molecular Weight564.65
FormulaC26H34F2N6O4S
Cas No.2410796-79-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (88.55 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7710 mL8.8550 mL17.7101 mL88.5504 mL
5 mM0.3542 mL1.7710 mL3.5420 mL17.7101 mL
10 mM0.1771 mL0.8855 mL1.7710 mL8.8550 mL
20 mM0.0886 mL0.4428 mL0.8855 mL4.4275 mL
50 mM0.0354 mL0.1771 mL0.3542 mL1.7710 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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