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Sovilnesib

🥰Excellent
Catalog No. T39994Cas No. 2410796-79-9
Alias AMG650

Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.

Sovilnesib

Sovilnesib

🥰Excellent
Purity: 98.59%
Catalog No. T39994Alias AMG650Cas No. 2410796-79-9
Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.
Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$247In Stock
10 mg$396In Stock
25 mg$663In Stock
50 mg$945In Stock
100 mg$1,280In Stock
1 mL x 10 mM (in DMSO)$272In Stock
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Purity:98.59%
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Product Introduction

Bioactivity
Description
Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.
In vitro
Sovilnesib is an inhibitor of the kinesin-like protein KIF18A[1].
AliasAMG650
Chemical Properties
Molecular Weight564.65
FormulaC26H34F2N6O4S
Cas No.2410796-79-9
SmilesCc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC3)CC2)nc(n1)N1CCC(F)(F)CC1
Relative Density.1.45 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (88.55 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7710 mL8.8550 mL17.7101 mL88.5504 mL
5 mM0.3542 mL1.7710 mL3.5420 mL17.7101 mL
10 mM0.1771 mL0.8855 mL1.7710 mL8.8550 mL
20 mM0.0886 mL0.4428 mL0.8855 mL4.4275 mL
50 mM0.0354 mL0.1771 mL0.3542 mL1.7710 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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