Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Subasumstat (TAK-981) is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 76.00 | |
2 mg | In stock | $ 108.00 | |
5 mg | In stock | $ 163.00 | |
10 mg | In stock | $ 255.00 | |
25 mg | In stock | $ 478.00 | |
50 mg | In stock | $ 689.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 198.00 |
Description | Subasumstat (TAK-981) is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities. |
In vitro | TAK-981 is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, TAK-981 activating innate effector cells and enhancing the antitumor innate immune responses[1]. |
In vivo | TAK-981(A single sub-cutaneous injection) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs[2]. |
Synonyms | TAK-981 |
Molecular Weight | 578.1 |
Formula | C25H28ClN5O5S2 |
CAS No. | 1858276-04-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 75 mg/mL (129.74 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Subasumstat 1858276-04-6 Ubiquitination E1/E2/E3 Enzyme inhibit Ubiquitin ligase E1 activating enzyme TAK-981 Ubiquitin conjugating enzyme TAK 981 Inhibitor E2 conjugating enzyme TAK981 Ubiquitin activating enzyme E3 ligating enzyme inhibitor