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Sulbactam

Catalog No. T1631   CAS 68373-14-8
Synonyms: CP45899

Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Sulbactam Chemical Structure
Sulbactam, CAS 68373-14-8
Pack Size Availability Price/USD Quantity
50 mg In stock $ 38.00
100 mg In stock $ 50.00
200 mg In stock $ 58.00
500 mg In stock $ 92.00
1 mL * 10 mM (in DMSO) In stock $ 47.00
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Purity: 99.32%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.
Synonyms CP45899
Molecular Weight 233.24
Formula C8H11NO5S
CAS No. 68373-14-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 43 mg/mL (184.4 mM)

DMSO: 44 mg/mL (188.6 mM)

Ethanol: 44 mg/mL (188.6 mM)

TargetMolReferences and Literature

1. Singh GS, et al. Mini Rev Med Chem. 2004 Jan;4(1):93-109.

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library Antibiotics Library Immunology/Inflammation Compound Library FDA-Approved Drug Library Anti-Infection Compound Library Beta-Lactam Compound Library High Solubility Fragment Library Bioactive Compounds Library Max ReFRAME Related Library Covalent Inhibitor Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sulbactam 68373-14-8 Microbiology/Virology Antibiotic Antibacterial bacteria inhibit CP45899 Bacterial CP-45899 multidrug-resistant CP 45899 complex MDR competitive irreversible Inhibitor inhibitor

 

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