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TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
2 mg | $38 | In Stock | |
5 mg | $63 | In Stock | |
10 mg | $97 | In Stock | |
25 mg | $198 | In Stock | |
50 mg | $298 | In Stock | |
100 mg | $445 | In Stock | |
1 mL x 10 mM (in DMSO) | $69 | In Stock |
Description | TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available. |
Targets&IC50 | TGR5 (human):0.72 nM |
Molecular Weight | 399.48 |
Formula | C25H25N3O2 |
Cas No. | 1415407-60-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (25.03 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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