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TLR4-IN-C34
🥰Excellent
Catalog No. T8503Cas No. 40592-88-9
TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis
TLR4-IN-C34
🥰Excellent
Purity: 99.77%
Catalog No. T8503Cas No. 40592-88-9
TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $38 | In Stock | |
| 5 mg | $61 | In Stock | |
| 10 mg | $85 | In Stock | |
| 25 mg | $133 | In Stock | |
| 50 mg | $215 | In Stock | |
| 100 mg | $318 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $68 | In Stock |
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Purity:99.77%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis |
| In vitro | TLR4-IN-C34 reduced systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. |
| Animal Research | Experimental NEC was induced in 7 8 day old mice .TLR4-IN-C34 was administered via the oral route at a concentration of 1 mg/kg on each morning of the four day model. |
| Molecular Weight | 389.4 |
| Formula | C17H27NO9 |
| Cas No. | 40592-88-9 |
| Smiles | CC(C)O[C@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1NC(C)=O |
| Relative Density. | 1.21 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 9 mg/mL (23.11 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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