Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 42.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 109.00 | |
25 mg | In stock | $ 233.00 | |
50 mg | In stock | $ 349.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM). |
Targets&IC50 | FLT3:320 nM ) , Tyro3:220 nM , Axl:120 nM, pMer TK:510 nM(EC50) |
Molecular Weight | 471.57 |
Formula | C24H34FN7O2 |
CAS No. | 1612782-86-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (21.21 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
UNC2541 1612782-86-1 Angiogenesis Others Tyrosine Kinase/Adaptors FLT TAM Receptor UNC 2541 Inhibitor UNC-2541 Tyro3 inhibit Mer Axl inhibitor