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Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $68 | In Stock | |
10 mg | $117 | In Stock | |
25 mg | $195 | In Stock | |
50 mg | $349 | In Stock | |
100 mg | $459 | In Stock | |
500 mg | $1,060 | In Stock | |
1 mL x 10 mM (in DMSO) | $48 | In Stock |
Description | Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. |
Targets&IC50 | 5-LOX:2.5 μM (IC50) |
Alias | IKK Inhibitor II |
Molecular Weight | 314.25 |
Formula | C16H10O7 |
Cas No. | 524-12-9 |
Smiles | COc1cc(O)c2c3oc4cc(O)c(O)cc4c3c(=O)oc2c1 |
Relative Density. | 1.655 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 20 mg/mL (63.64 mM), Sonication is recommended. ![]() Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble | ||||||||||||||||||||||||||||||
In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5.7 mg/mL (18.14 mM), In vivo: Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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