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YH-306

Catalog No. T24642Cas No. 1373764-75-0
Alias YH306, TRV055 acetate (25849-90-5 Free base)

YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.

YH-306

YH-306

Purity: 97.87%
Catalog No. T24642Alias YH306, TRV055 acetate (25849-90-5 Free base)Cas No. 1373764-75-0
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
Pack SizePriceAvailabilityQuantity
5 mg$29In Stock
10 mg$48In Stock
25 mg$98In Stock
50 mg$148In Stock
100 mg$223In Stock
200 mg$329In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:97.87%
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Product Introduction

Bioactivity
Description
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
In vitro
YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1, and the expression of MMP2 and MMP9. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 inhibits Arp2/3 complex-mediated actin polymerization[1].
AliasYH306, TRV055 acetate (25849-90-5 Free base)
Chemical Properties
Molecular Weight306.36
FormulaC19H18N2O2
Cas No.1373764-75-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 15 mg/mL (48.96 mM), when pH is adjusted to 1 with HCl. Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2641 mL16.3207 mL32.6413 mL163.2067 mL
5 mM0.6528 mL3.2641 mL6.5283 mL32.6413 mL
10 mM0.3264 mL1.6321 mL3.2641 mL16.3207 mL
20 mM0.1632 mL0.8160 mL1.6321 mL8.1603 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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