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YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $29 | In Stock | |
10 mg | $48 | In Stock | |
25 mg | $98 | In Stock | |
50 mg | $148 | In Stock | |
100 mg | $223 | In Stock | |
200 mg | $329 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis. |
In vitro | YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1, and the expression of MMP2 and MMP9. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 inhibits Arp2/3 complex-mediated actin polymerization[1]. |
Alias | YH306, TRV055 acetate (25849-90-5 Free base) |
Molecular Weight | 306.36 |
Formula | C19H18N2O2 |
Cas No. | 1373764-75-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 15 mg/mL (48.96 mM), when pH is adjusted to 1 with HCl. Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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