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YH-306

YH-306
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
Catalog No. T24642Cas No. 1373764-75-0
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Purity:97.87%
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YH-306

Catalog No. T24642Cas No. 1373764-75-0
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$29In Stock
10 mg$48In Stock
25 mg$98In Stock
50 mg$148In Stock
100 mg$223In Stock
200 mg$329In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Product Introduction

Bioactivity
Description
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
In vitro
YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1, and the expression of MMP2 and MMP9. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 inhibits Arp2/3 complex-mediated actin polymerization[1].
AliasYH306, TRV055 acetate (25849-90-5 Free base)
Chemical Properties
Molecular Weight306.36
FormulaC19H18N2O2
Cas No.1373764-75-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 15 mg/mL (48.96 mM), when pH is adjusted to 1 with HCl. Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2641 mL16.3207 mL32.6413 mL163.2067 mL
5 mM0.6528 mL3.2641 mL6.5283 mL32.6413 mL
10 mM0.3264 mL1.6321 mL3.2641 mL16.3207 mL
20 mM0.1632 mL0.8160 mL1.6321 mL8.1603 mL

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