Powder: -20°C for 3 years | In solvent: -80°C for 1 year
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholesteryl esters.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 84.00 | |
10 mg | In stock | $ 139.00 | |
25 mg | In stock | $ 278.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 672.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 93.00 |
Description | YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholesteryl esters. |
Synonyms | YM 750 |
Molecular Weight | 452.63 |
Formula | C31H36N2O |
CAS No. | 138046-43-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (220.93 mM), Sonication is recommended.
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
YM-750 138046-43-2 Metabolism Acyltransferase stress Inhibitor cells Diacylglycerol acyltransferase mono- acylglycerol acyltransferase Diglyceride acyltransferase cholesterol inhibit foam acyl-CoA:cholesterol acyltransferase anti-hyperlipidemic oxidative levels anti-atherosclerotic YM750 YM 750 inhibitor