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Amezinium methylsulfate
🥰Excellent
Catalog No. T5327Cas No. 30578-37-1
Alias Lu-1631, Amezinium metilsulfate, Amezinium (methylsulfate)
Amezinium methylsulfate (Lu-1631) has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.
Amezinium methylsulfate
🥰Excellent
Purity: 99.64%
Catalog No. T5327Alias Lu-1631, Amezinium metilsulfate, Amezinium (methylsulfate)Cas No. 30578-37-1
Amezinium methylsulfate (Lu-1631) has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $48 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $50 | In Stock |
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Purity:99.64%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Amezinium methylsulfate (Lu-1631) has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake. |
| In vivo | In 5 patients with multiple system atrophy, administration of 15 mg/day of amezinium metilsulfate, an adrenergic agent, during 6 months for the treatment of postural hypotension exacerbated post-micturition residuals as compared to that before treatment (178 ml versus 113 ml for a change of 37 %) [1]. The reduction ratio of FTBF was significantly increased by amezimium [placebo, 75.9%; amezinium, 85.1%; midodrine, 78.1%]. The infusion rate of noradrenaline producing a half-maximum venoconstriction was significantly decreased by amezinium (placebo, 40.6 ng/min; amezinium, 21.0 ng/min) [2]. |
| Alias | Lu-1631, Amezinium metilsulfate, Amezinium (methylsulfate) |
| Molecular Weight | 313.33 |
| Formula | C12H15N3O5S |
| Cas No. | 30578-37-1 |
| Smiles | COS([O-])(=O)=O.COc1cc(N)cn[n+]1-c1ccccc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (159.58 mM)  | |||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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