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Anisodamine
🥰Excellent
Catalog No. T21532Cas No. 55869-99-3
Alias 6-Hydroxyhyoscyamine, 6-beta-Hydroxyhyoscyamine
Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning.
Anisodamine
🥰Excellent
Purity: 98.63%
Catalog No. T21532Alias 6-Hydroxyhyoscyamine, 6-beta-HydroxyhyoscyamineCas No. 55869-99-3
Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $97 | In Stock | |
| 5 mg | $313 | In Stock | |
| 10 mg | $468 | In Stock | |
| 25 mg | $753 | In Stock | |
| 50 mg | $987 | In Stock | |
| 100 mg | $1,390 | In Stock | |
| 500 mg | $2,790 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $278 | In Stock |
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Purity:98.63%
ee:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning. |
| In vitro | In RAW264.7 cells, Anisodamine (100 μg/mL) blocks muscarinic receptors thus allowing more endogenous ACh binding to the α-7nAChR and attenuating α-bungarotoxin binding[3]. |
| In vivo | Intraperitoneal administration of Anisodamine (50 mg/kg) significantly reduces mortality of LPS-induced shock mice(20%)[3]. |
| Alias | 6-Hydroxyhyoscyamine, 6-beta-Hydroxyhyoscyamine |
| Molecular Weight | 305.37 |
| Formula | C17H23NO4 |
| Cas No. | 55869-99-3 |
| Smiles | CN1[C@@H]2C[C@H](O)[C@H]1C[C@H](C2)OC(=O)[C@H](CO)c1ccccc1 |
| Relative Density. | 1.27 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90.0 mg/mL (294.7 mM) H2O: 18.0 mg/mL (58.9 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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