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AWZ1066S

🥰Excellent
Catalog No. T10423Cas No. 2239272-16-1

AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).

AWZ1066S

AWZ1066S

🥰Excellent
Purity: 98.32%
Catalog No. T10423Cas No. 2239272-16-1
AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).
Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
5 mg$98In Stock
10 mg$173In Stock
25 mg$289In Stock
50 mg$414In Stock
100 mg$595In Stock
1 mL x 10 mM (in DMSO)$111In Stock
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Purity:98.32%
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Product Introduction

Bioactivity
Description
AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).
Chemical Properties
Molecular Weight404.39
FormulaC19H19F3N6O
Cas No.2239272-16-1
SmilesC[C@H]1COCCN1c1nc(NCc2cccnc2C(F)(F)F)c2cccnc2n1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (296.74 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4729 mL12.3643 mL24.7286 mL123.6430 mL
5 mM0.4946 mL2.4729 mL4.9457 mL24.7286 mL
10 mM0.2473 mL1.2364 mL2.4729 mL12.3643 mL
20 mM0.1236 mL0.6182 mL1.2364 mL6.1822 mL
50 mM0.0495 mL0.2473 mL0.4946 mL2.4729 mL
100 mM0.0247 mL0.1236 mL0.2473 mL1.2364 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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