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Azaphen dihydrochloride monohydrate

🥰Excellent
Catalog No. T61741Cas No. 63302-99-8
Alias Pipofezin dihydrochloride monohydrate, Azaphenonxazine dihydrochloride monohydrate, Azafen dihydrochloride monohydrate

Azaphen dihydrochloride monohydrate (Pipofezin dihydrochloride monohydrate) is a serotonin reuptake inhibitor with antidepressant activity and sedative effects, which can be used to study neurological diseases.

Azaphen dihydrochloride monohydrate

Azaphen dihydrochloride monohydrate

🥰Excellent
Purity: 99.85%
Catalog No. T61741Alias Pipofezin dihydrochloride monohydrate, Azaphenonxazine dihydrochloride monohydrate, Azafen dihydrochloride monohydrateCas No. 63302-99-8
Azaphen dihydrochloride monohydrate (Pipofezin dihydrochloride monohydrate) is a serotonin reuptake inhibitor with antidepressant activity and sedative effects, which can be used to study neurological diseases.
Pack SizePriceAvailabilityQuantity
10 mg$37In Stock
25 mg$59In Stock
50 mg$86In Stock
100 mg$126In Stock
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Purity:99.85%
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Product Introduction

Bioactivity
Description
Azaphen dihydrochloride monohydrate (Pipofezin dihydrochloride monohydrate) is a serotonin reuptake inhibitor with antidepressant activity and sedative effects, which can be used to study neurological diseases.
In vitro
The suppression of 5-HT uptake by Azaphen dihydrochloride monohydrate reduced the tumourigenicity and inhibited the distant metastasis of NSCLC cells in vivo, underscoring the importance of SERT in tumourigenesis. [1]
AliasPipofezin dihydrochloride monohydrate, Azaphenonxazine dihydrochloride monohydrate, Azafen dihydrochloride monohydrate
Chemical Properties
Molecular Weight388.29
FormulaC16H23Cl2N5O2
Cas No.63302-99-8
SmilesCN1C2=C(C=CC=C2)OC3=NN=C(N4CCN(CC4)C)C=C31.Cl.O.Cl
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 1 mg/mL (2.58 mM), Sonication is recommended.
H2O: 80 mg/mL (206.03 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.5754 mL12.8770 mL25.7539 mL128.7697 mL
H2O
1mg5mg10mg50mg
5 mM0.5151 mL2.5754 mL5.1508 mL25.7539 mL
10 mM0.2575 mL1.2877 mL2.5754 mL12.8770 mL
20 mM0.1288 mL0.6438 mL1.2877 mL6.4385 mL
50 mM0.0515 mL0.2575 mL0.5151 mL2.5754 mL
100 mM0.0258 mL0.1288 mL0.2575 mL1.2877 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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