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Benzydamine hydrochloride

Catalog No. T0726Cas No. 132-69-4
Alias Benzydamine HCl, AF864

Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.

Benzydamine hydrochloride

Benzydamine hydrochloride

Purity: 98.42%
Catalog No. T0726Alias Benzydamine HCl, AF864Cas No. 132-69-4
Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.
Pack SizePriceAvailabilityQuantity
50 mg$33In Stock
100 mg$47In Stock
200 mg$60In Stock
500 mg$95In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:98.42%
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Product Introduction

Bioactivity
Description
Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.
In vivo
Benzydamine significantly lower the incidence of postoperative sore throat (POST). At 6 hours after extubation, the incidence of POST is 17.0%. Spraying benzydamine hydrochloride on the ETT cuff is a simple and effective method to reduce the incidence and severity of POST. [2]
AliasBenzydamine HCl, AF864
Chemical Properties
Molecular Weight345.87
FormulaC19H23N3O·HCl
Cas No.132-69-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (130.11 mM), Sonication is recommended.
Ethanol: 64 mg/mL (185 mM)
H2O: 63 mg/mL (182.1 mM)
Solution Preparation Table
DMSO/H2O/Ethanol
1mg5mg10mg50mg
1 mM2.8913 mL14.4563 mL28.9126 mL144.5630 mL
5 mM0.5783 mL2.8913 mL5.7825 mL28.9126 mL
10 mM0.2891 mL1.4456 mL2.8913 mL14.4563 mL
20 mM0.1446 mL0.7228 mL1.4456 mL7.2281 mL
50 mM0.0578 mL0.2891 mL0.5783 mL2.8913 mL
100 mM0.0289 mL0.1446 mL0.2891 mL1.4456 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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