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Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 93 € | In Stock | |
5 mg | 188 € | In Stock | |
10 mg | 283 € | In Stock | |
25 mg | 452 € | In Stock | |
50 mg | 644 € | In Stock | |
100 mg | 866 € | In Stock | |
200 mg | 1.130 € | In Stock | |
1 mL x 10 mM (in DMSO) | 217 € | In Stock |
Description | Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction. |
Targets&IC50 | Ca2+ channel, N-type:14.23 μM (EC50), CDK2:3.34 μM (EC50) |
In vitro | Ca2+ channel agonist 1 (Compound 13d) exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine. |
Molecular Weight | 354.45 |
Formula | C19H26N6O |
Cas No. | 1402821-24-2 |
Smiles | CCCn1cnc2c(NCc3ccccc3)nc(N[C@H](CC)CO)nc12 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (126.96 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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