Shopping Cart
- Remove All
Your shopping cart is currently empty
Calcifediol
🥰Excellent
Catalog No. T6430Cas No. 19356-17-3
Alias U 32070E, RO 8-8892, 25-hydroxy Vitamin D3
Calcifediol (U 32070E) is a naturally occurring product that is metabolized in the liver from vitamin D3, a VDR ligand. Calcifediol is indicated for use as a vitamin supplement for all patients with vitamin D deficiency.
Calcifediol
🥰Excellent
Purity: 99.28%
Catalog No. T6430Alias U 32070E, RO 8-8892, 25-hydroxy Vitamin D3Cas No. 19356-17-3
Calcifediol (U 32070E) is a naturally occurring product that is metabolized in the liver from vitamin D3, a VDR ligand. Calcifediol is indicated for use as a vitamin supplement for all patients with vitamin D deficiency.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $44 | In Stock | |
| 5 mg | $97 | In Stock | |
| 10 mg | $155 | In Stock | |
| 25 mg | $313 | In Stock | |
| 50 mg | $513 | In Stock | |
| 100 mg | $747 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $118 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Calcifediol"
Glycerol
Glycerin
T477656-81-5
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol is an important component of trigl
- $41
Size
QTY
Sucrose
D(+)-Sucrose, D-(+)-Saccharose
T473357-50-1
Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
- $29
Size
QTY
Thymidine
Cited
Thymidin, NSC 21548, DThyd, Deoxyribothymidine, 5-Methyldeoxyuridine
TWP291150-89-5
Thymidine (DThyd) is a cell synchronizing agent and a specific precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis and can cause cell cycle arrest in the G1/S phase.
- $45
Size
QTY
Cited3-Indoleacetic acid Cited
indolylacetic acid, indoleacetic acid, Indole-3-acetic acid, IAA, 3-IAA, 1H-Indole-3-acetic acid
T2O279187-51-4
3-Indoleacetic acid (indolylacetic acid) (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.
- $41
Size
QTY
CitedFerulic Acid Cited
Fumalic Acid, Coniferic acid
T22151135-24-6
Ferulic Acid (Coniferic acid) is a highly abundant phenolic phytochemical and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong.It can be absorbed by the small intestine and excreted through the urine.
- $30
Size
QTY
CitedDaidzein Cited
Isoflavone
T1238486-66-8
Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties.
- $45
Size
QTY
CitedGuanidine hydrochloride
Guanidinium chloride, Guanidine HCl, Aminoformamidine Hydrochloride, Aminoformamidine HCl
T041550-01-1
Guanidine hydrochloride (Aminoformamidine Hydrochloride) is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.
- $29
Size
QTY
Naringin Cited
Naringoside
T059510236-47-2
Naringin (Naringoside), a flavanone glycoside, exerts various of pharmacological effects such as blood lipid lowering, antioxidant activity, anticancer activity, and inhibition of cytochrome P450 enzymes.
- $35
Size
QTY
CitedFumaric acid
Trans-Butenedioic acid, Lichenic acid, Fumarate, Donitic acid, Allomaleic acid, 2-Butenedioic acid
T3763110-17-8
Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes.
- $32
Size
QTY
Oleamide
Oleic acid amide
T13802301-02-0
Oleamide (Oleic acid amide) is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system.
- $50
Size
QTY
Oxalic acid dihydrate
Ethanedioic acid dihydrate
T50646153-56-6
Oxalic acid dihydrate (Ethanedioic acid dihydrate) is a strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
- $39
Size
QTY
p-Hydroxybenzaldehyde
p-Oxybenzaldehyde, 4-hydroxybenzaldehyde, 4-Formylphenol
T2S1814123-08-0
1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic acid, a known anticonvulsant.
- $47
Size
QTY
Select Batch
Purity:99.28%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Calcifediol (U 32070E) is a naturally occurring product that is metabolized in the liver from vitamin D3, a VDR ligand. Calcifediol is indicated for use as a vitamin supplement for all patients with vitamin D deficiency. |
| Targets&IC50 | PTH:2 nM(ED50), Vitamin D3:3.9 μM(ki) |
| In vitro | Calcifediol, whether in liposomes or ethanolic solution, does not affect the release of the proinflammatory cytokine KC from Pseudomonas-infected murine epithelial cells. However, treating infected human bronchial 16-HBE cells with Calcifediol liposomes significantly reduces bacterial survival [1]. |
| In vivo | METHODS: Calcifediol (25 µg/kg) was administered dietary to rats for four weeks to study its role in pregnancy. RESULTS: Calcifediol provided better vitamin D availability to the mother and fetus when administered during pregnancy compared to vitamin D3. No adverse effects on pregnancy outcome were observed, and further studies are needed to investigate the effects of Calcifediol on fetal brain VDR and GAD67 expression. [3] |
| Alias | U 32070E, RO 8-8892, 25-hydroxy Vitamin D3 |
| Molecular Weight | 400.64 |
| Formula | C27H44O2 |
| Cas No. | 19356-17-3 |
| Smiles | [H][C@@]12CC[C@H]([C@H](C)CCCC(C)(C)O)[C@@]1(C)CCC\C2=C/C=C1/C[C@H](O)CCC1=C |
| Relative Density. | 1.01 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 18.33 mg/mL (45.76 mM)  Ethanol: 16 mg/mL (39.9 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
Ethanol/DMSO
| ||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Calcifediol | purchase Calcifediol | Calcifediol cost | order Calcifediol | Calcifediol chemical structure | Calcifediol in vivo | Calcifediol in vitro | Calcifediol formula | Calcifediol molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.