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CID 5951923
Catalog No. T22667Cas No. 749872-43-3
CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
CID 5951923
Catalog No. T22667Cas No. 749872-43-3
CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $32 | In Stock | |
| 5 mg | $53 | In Stock | |
| 10 mg | $68 | In Stock | |
| 25 mg | $131 | In Stock | |
| 50 mg | $233 | In Stock | |
| 100 mg | $349 | In Stock | |
| 200 mg | $498 | In Stock |
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Purity:100.00%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM. |
| Targets&IC50 | KLF5:603 nM (IC50) |
| In vitro | CID 5951923 (10 μM) inhibits the proliferation of cancer cell lines mainly in highly expressing KLF5 cells. CID 5951923 (0.001, 0.01, 0.1, 1, 10, 100 μM) inhibits proliferation of DLD-1 cells in a dose-dependent manner. CID 5951923 (10 μM) significantly decreases endogenous KLF5 levels in the DLD-1 cells, downregulates EGR1, and increases phosphorylation levels of pEGFFpY1068[1]. |
| Molecular Weight | 382.39 |
| Formula | C16H18N2O7S |
| Cas No. | 749872-43-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.82 mg/mL (10 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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