Shopping Cart
- Remove All
Your shopping cart is currently empty
Co 101244 hydrochloride
🥰Excellent
Catalog No. T22674Cas No. 193356-17-1
Alias 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride
Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist.
Co 101244 hydrochloride
🥰Excellent
Purity: 98.44%
Catalog No. T22674Alias 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochlorideCas No. 193356-17-1
Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $35 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $95 | In Stock | |
| 25 mg | $193 | In Stock | |
| 50 mg | $297 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Co 101244 hydrochloride"
Riluzole
RP-54274, PK 26124
T03491744-22-5
Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
- $45
Size
QTY
Halothane
Narcotane, Anestan
T0954151-67-7
Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required.
- $45
Size
QTY
O-Phospho-L-serine
Phosphoserine, L-SOP, L-Serine O-phosphate, Dexfosfoserine
T1324407-41-0
O-Phospho-L-serine (Phosphoserine) is the phosphoric acid ester of serine.
- $33
Size
QTY
Mephenesin
Mephedan, Memphenesin, Decontractyl, Cresoxydiol
T001559-47-2
Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.
- $33
Size
QTY
Procaine hydrochloride
Procaine HCl, Novocaine HCl
T080251-05-8
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.
- $31
Size
QTY
(-)-Aspartic acid
D-Aspartic acid, D-(-)-Aspartic acid, asparagic acid, Asp, Aminosuccinic acid
T48851783-96-6
(-)-Aspartic acid (L-Homoproline) is an endogenous amino acid existing in invertebrates and vertebrates. It can regulate testosterone synthesis and is an agonist of NMDA receptor.
- $41
Size
QTY
1-Aminocyclopropane-1-carboxylic acid
ACC, 1-Aminocyclopropanecarboxylic acid, 1-Amino-1-carboxycyclopropane
T475222059-21-8
1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecule agonist at the glycine modulatory site of the NMDA receptor (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate.2 This compound has been reported to protect against neuron cell death in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.
- $30
Size
QTY
Memantine hydrochloride
Cited
Namenda, Memantine HCl, D-145 (hydrochloride)
T144341100-52-1
Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
- $42
Size
QTY
CitedQuinolinic acid
QUIN, pyridine-2,3-dicarboxylic acid
T409689-00-9
Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
- $41
Size
QTY
Bupivacaine hydrochloride monohydrate
T8064173360-54-0
Bupivacaine hydrochloride monohydrate is a potent NMDA receptor inhibitor of sodium, L-calcium, and potassium channels.Bupivacaine hydrochloride monohydrate inhibits SCN5A channels and is commonly used in the study of chronic pain.
- $195
Size
QTY
Ifenprodil Tartrate
T118623210-58-4
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
- $50
Size
QTY
Select Batch
Purity:98.44%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist. |
| In vitro | Co 101244 enhances neuroprotection and reduces NMDA-evoked Ca2+?elevations effectively [1]. |
| In vivo | Administration of 1 mg/kg s.c. Co 101244 displayed antidyskinetic effects with the reduction of 67% while sparing levodopa motor benefit[1]. |
| Alias | 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride |
| Molecular Weight | 377.9 |
| Formula | C21H28ClNO3 |
| Cas No. | 193356-17-1 |
| Smiles | Cc1ccc(CC2(CCN(CCOc(cc3)ccc3O)CC2)O)cc1.Cl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: < 35 mg/mL (92.62 mM) DMSO: 50 mg/mL (132.31 mM)  | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
| |||||||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Co 101244 hydrochloride | purchase Co 101244 hydrochloride | Co 101244 hydrochloride cost | order Co 101244 hydrochloride | Co 101244 hydrochloride chemical structure | Co 101244 hydrochloride in vivo | Co 101244 hydrochloride in vitro | Co 101244 hydrochloride formula | Co 101244 hydrochloride molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.