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DHODH-IN-23

Catalog No. T67875Cas No. 1346705-53-0

DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.

DHODH-IN-23

DHODH-IN-23

Purity: 98.1%
Catalog No. T67875Cas No. 1346705-53-0
DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
Pack SizePriceAvailabilityQuantity
5 mg$48In Stock
10 mg$76In Stock
25 mg$173In Stock
50 mg$273In Stock
100 mg$395In Stock
500 mgInquiryIn Stock
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Purity:98.1%
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Product Introduction

Bioactivity
Description
DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
In vitro
DHODH-IN-23 (72 h) inhibits proliferation of acute myeloid leukemia cells.[1]
DHODH-IN-23 (0.1-3 μM; 72 h) induces the expression of CDllb in THP-1 cells.[1]
In vivo
DHODH-IN-23 (30 mg/kg; oral; twice daily for 21 days) exhibits anti-tumor activity in the MV411 xenograft mouse model.[1]
Chemical Properties
Molecular Weight441.88
FormulaC24H21ClFNO4
Cas No.1346705-53-0
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 112.5 mg/mL (254.6 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2631 mL11.3153 mL22.6306 mL113.1529 mL
5 mM0.4526 mL2.2631 mL4.5261 mL22.6306 mL
10 mM0.2263 mL1.1315 mL2.2631 mL11.3153 mL
20 mM0.1132 mL0.5658 mL1.1315 mL5.6576 mL
50 mM0.0453 mL0.2263 mL0.4526 mL2.2631 mL
100 mM0.0226 mL0.1132 mL0.2263 mL1.1315 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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