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Fabomotizole hydrochloride

🥰Excellent
Catalog No. T4093Cas No. 173352-39-1
Alias CM346 hydrochloride, Afobazole hydrochloride

Fabomotizole hydrochloride (CM346 hydrochloride), an anxiolytic drug, produces anxiolytic and neuroprotective effects. The mechanism of Afobazole remains poorly defined, however, with GABAergic, NGF, and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole inhibits MAO-A reversibly and there might be also some involvement with serotonin receptors.

Fabomotizole hydrochloride

Fabomotizole hydrochloride

🥰Excellent
Purity: 100%
Catalog No. T4093Alias CM346 hydrochloride, Afobazole hydrochlorideCas No. 173352-39-1
Fabomotizole hydrochloride (CM346 hydrochloride), an anxiolytic drug, produces anxiolytic and neuroprotective effects. The mechanism of Afobazole remains poorly defined, however, with GABAergic, NGF, and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole inhibits MAO-A reversibly and there might be also some involvement with serotonin receptors.
Pack SizePriceAvailabilityQuantity
2 mg$35In Stock
5 mg$56In Stock
10 mg$98In Stock
25 mg$218In Stock
50 mg$372In Stock
100 mg$619In Stock
500 mg$1,280In Stock
1 mL x 10 mM (in DMSO)$62In Stock
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Purity:100%
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Description
Fabomotizole hydrochloride (CM346 hydrochloride), an anxiolytic drug, produces anxiolytic and neuroprotective effects. The mechanism of Afobazole remains poorly defined, however, with GABAergic, NGF, and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole inhibits MAO-A reversibly and there might be also some involvement with serotonin receptors.
AliasCM346 hydrochloride, Afobazole hydrochloride
Chemical Properties
Molecular Weight343.87
FormulaC15H22ClN3O2S
Cas No.173352-39-1
SmilesCl.CCOc1ccc2nc(SCCN3CCOCC3)[nH]c2c1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (145.4 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9081 mL14.5404 mL29.0808 mL145.4038 mL
5 mM0.5816 mL2.9081 mL5.8162 mL29.0808 mL
10 mM0.2908 mL1.4540 mL2.9081 mL14.5404 mL
20 mM0.1454 mL0.7270 mL1.4540 mL7.2702 mL
50 mM0.0582 mL0.2908 mL0.5816 mL2.9081 mL
100 mM0.0291 mL0.1454 mL0.2908 mL1.4540 mL

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