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Fluspirilene
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Fluspirilene
Catalog No. T15301Cas No. 1841-19-6
Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $35 | In Stock | |
| 5 mg | $81 | In Stock | |
| 10 mg | $123 | In Stock | |
| 25 mg | $222 | In Stock | |
| 50 mg | $333 | In Stock | |
| 100 mg | $493 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $85 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia. |
| In vitro | Fluspirilene (1.25, 2.5, and 5 μM) demonstrates the inhibition of proliferation of T98, U87, and all GSC lines, while Fluspirilene (2.5 and 5 μM) inhibits the proliferation of U251 and SNB19.[2] Fluspirilene decreases the viability and suppresses the sphere-forming of glioma stem cell lines in a dose-dependent manner.[2] |
| In vivo | Fluspirilene obviously prolongs the survival of the TGS04 mouse model. Mice treated with fluspirilene display a remarkable reduction in tumor size.[2] |
| Alias | Redeptin, R 6218 |
| Molecular Weight | 475.57 |
| Formula | C29H31F2N3O |
| Cas No. | 1841-19-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (63.08 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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