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Gliclazide

Catalog No. T1527Cas No. 21187-98-4
Alias SE1702, S1702

Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the pancreas to release insulin.

Gliclazide

Gliclazide

Purity: 98.08%
Catalog No. T1527Alias SE1702, S1702Cas No. 21187-98-4
Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the pancreas to release insulin.
Pack SizePriceAvailabilityQuantity
500 mg$45In Stock
1 g$71In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:98.08%
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Product Introduction

Bioactivity
Description
Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the pancreas to release insulin.
Targets&IC50
K+ channel:184 nM
AliasSE1702, S1702
Chemical Properties
Molecular Weight323.41
FormulaC15H21N3O3S
Cas No.21187-98-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 45 mg/mL (139.14 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0921 mL15.4603 mL30.9205 mL154.6025 mL
5 mM0.6184 mL3.0921 mL6.1841 mL30.9205 mL
10 mM0.3092 mL1.5460 mL3.0921 mL15.4603 mL
20 mM0.1546 mL0.7730 mL1.5460 mL7.7301 mL
50 mM0.0618 mL0.3092 mL0.6184 mL3.0921 mL
100 mM0.0309 mL0.1546 mL0.3092 mL1.5460 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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