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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $74 | In Stock | |
2 mg | $108 | In Stock | |
5 mg | $178 | In Stock | |
10 mg | $322 | In Stock | |
25 mg | $522 | In Stock | |
50 mg | $759 | In Stock | |
100 mg | $1,060 | In Stock | |
500 mg | $2,130 | In Stock | |
1 mL x 10 mM (in DMSO) | $197 | In Stock |
Description | ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavorable prognosis. |
Targets&IC50 | Others:8.6 μM |
In vitro | ICCB280 (10 μM; 2-8 d) increases the C/EBPα expression (mRNA and protein) and modulates its target genes in HL-60 cells.ICCB280 (0.1-50 μM; 48 h) suppresses the HL-60 cell growth, with an IC50 of 8.6 μM[1]. |
Molecular Weight | 386.4 |
Formula | C23H18N2O4 |
Cas No. | 2041072-41-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (142.34 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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