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Inarigivir soproxil
🥰Excellent
Catalog No. T15573Cas No. 942123-43-5
Alias SB9200
Inarigivir soproxil (SB9200) is an agonist of innate immunity that demonstrates effective antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems.
Inarigivir soproxil
🥰Excellent
Purity: 98.44%
Catalog No. T15573Alias SB9200Cas No. 942123-43-5
Inarigivir soproxil (SB9200) is an agonist of innate immunity that demonstrates effective antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $163 | In Stock | |
| 5 mg | $328 | In Stock | |
| 10 mg | $496 | In Stock | |
| 25 mg | $845 | In Stock | |
| 50 mg | $1,160 | In Stock | |
| 100 mg | $1,570 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $512 | In Stock |
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Purity:98.44%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Inarigivir soproxil (SB9200) is an agonist of innate immunity that demonstrates effective antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. |
| Targets&IC50 | HCV 1a/1b:(EC50)2.2/1.0 μM |
| In vitro | Inarigivir soproxil is shown to inhibit HCV replication and the range of inhibition is comparable between genotypes 1a and 1b. Inarigivir soproxil is an oral modulator of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. Inarigivir soproxil demonstrates pan-genotypic antiviral activity against HCV. Inarigivir soproxil is active against DAA-resistant HCV variants. SB 9200 has broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV)[1]. |
| Alias | SB9200 |
| Molecular Weight | 703.62 |
| Formula | C25H34N7O13PS |
| Cas No. | 942123-43-5 |
| Smiles | O(C)[C@H]1[C@@H](O[C@H](CO)[C@H]1OP(OC[C@H]2O[C@H](C[C@@H]2O)N3C=4C(N=C3)=C(N)N=CN4)(SCOC(OC(C)C)=O)=O)N5C(=O)NC(=O)C=C5 |
| Relative Density. | 1.80 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 102 mg/mL (144.96 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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