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kb-NB77-78

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Purity:99.89%

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COA HNMR LCMS

kb-NB77-78

Catalog No. T1808Cas No. 1350622-33-1

kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).

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Pack Size	Price	Availability
1 mg	$47	In Stock
2 mg	$80	In Stock
5 mg	$122	In Stock
10 mg	$198	In Stock
25 mg	$443	In Stock
50 mg	$656	In Stock
100 mg	$933	In Stock
1 mL x 10 mM (in DMSO)	$148	In Stock

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Product Introduction

Bioactivity

Description

kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).

Chemical Properties

Molecular Weight	331.48
Formula	C18H25NO3Si
Cas No.	1350622-33-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (135.75 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0168 mL	15.0839 mL	30.1677 mL	150.8387 mL
5 mM	0.6034 mL	3.0168 mL	6.0335 mL	30.1677 mL
10 mM	0.3017 mL	1.5084 mL	3.0168 mL	15.0839 mL
20 mM	0.1508 mL	0.7542 mL	1.5084 mL	7.5419 mL
50 mM	0.0603 mL	0.3017 mL	0.6034 mL	3.0168 mL
100 mM	0.0302 mL	0.1508 mL	0.3017 mL	1.5084 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc