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FOY 251

🥰Excellent
Catalog No. T8676Cas No. 71079-09-9

FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.

FOY 251

FOY 251

🥰Excellent
Purity: 99.33%
Catalog No. T8676Cas No. 71079-09-9
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
Pack SizePriceAvailabilityQuantity
1 mg$49In Stock
5 mg$118In Stock
10 mg$196In Stock
25 mg$334In Stock
50 mg$472In Stock
100 mg$672In Stock
500 mg$1,330In Stock
1 mL x 10 mM (in DMSO)$135In Stock
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Purity:99.33%
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Product Introduction

Bioactivity
Description
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
In vitro
FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats.?Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro[1].
Chemical Properties
Molecular Weight409.41
FormulaC17H19N3O7S
Cas No.71079-09-9
SmilesCS(O)(=O)=O.NN=CNc1ccc(cc1)C(=O)Oc1ccc(CC(O)=O)cc1
Relative Density.1.36g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (61.06 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4425 mL12.2127 mL24.4254 mL122.1270 mL
5 mM0.4885 mL2.4425 mL4.8851 mL24.4254 mL
10 mM0.2443 mL1.2213 mL2.4425 mL12.2127 mL
20 mM0.1221 mL0.6106 mL1.2213 mL6.1063 mL
50 mM0.0489 mL0.2443 mL0.4885 mL2.4425 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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