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L-694,247
🥰Excellent
Catalog No. T19701Cas No. 137403-12-4
Alias L694247, L694,247, L 694,247
L-694,247 is a selective 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases.
L-694,247
🥰Excellent
Purity: 98.36%
Catalog No. T19701Alias L694247, L694,247, L 694,247Cas No. 137403-12-4
L-694,247 is a selective 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $75 | In Stock | |
| 5 mg | $278 | In Stock | |
| 10 mg | $475 | In Stock | |
| 25 mg | $779 | In Stock | |
| 50 mg | $1,090 | In Stock |
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Purity:98.36%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | L-694,247 is a selective 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases. |
| Targets&IC50 | 5-HTIB:9.1 (pIC50), [125I]-GTI-5-HTID:10.0 (pIC50) |
| In vitro | L-694,247 displayed very high affinity (pIC50 = 10.0) for the 5-HTID site labelled with [125I]-GTI and was some 65-fold more potent in this regard than sumatriptan. It displayed somewhat lower affinity for the 5-HTIB binding site (pIC50 = 9.1) compared with the corresponding pIC50 value of 6.0 obtained with sumatriptan. [3] |
| Alias | L694247, L694,247, L 694,247 |
| Molecular Weight | 411.48 |
| Formula | C20H21N5O3S |
| Cas No. | 137403-12-4 |
| Smiles | O=S(=O)(NC1=CC=C(C=C1)CC2=NOC(=N2)C3=CC=C4NC=C(C4=C3)CCN)C |
| Relative Density. | 1.405g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (48.61 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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