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Levobupivacaine

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Catalog No. T1787Cas No. 27262-47-1

Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur.

Levobupivacaine

Levobupivacaine

🥰Excellent
Purity: 99.70%
Catalog No. T1787Cas No. 27262-47-1
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur.
Pack SizePriceAvailabilityQuantity
5 mg$40In Stock
10 mg$57In Stock
25 mg$94In Stock
50 mg$138In Stock
100 mg$198In Stock
200 mg$297In Stock
500 mg$512In Stock
1 mL x 10 mM (in DMSO)$42In Stock
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Purity:99.70%
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Product Introduction

Bioactivity
Description
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur.
Chemical Properties
Molecular Weight288.43
FormulaC18H28N2O
Cas No.27262-47-1
SmilesC(NC1=C(C)C=CC=C1C)(=O)[C@H]2N(CCCC)CCCC2
Relative Density.1.0238 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 6 mg/mL (20.8 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4670 mL17.3352 mL34.6705 mL173.3523 mL
5 mM0.6934 mL3.4670 mL6.9341 mL34.6705 mL
10 mM0.3467 mL1.7335 mL3.4670 mL17.3352 mL
20 mM0.1734 mL0.8668 mL1.7335 mL8.6676 mL

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