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MIK665 (S-64315) (S-64315) has an inhibitory effect on myeloid leukemia.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $135 | In Stock | |
5 mg | $289 | In Stock | |
10 mg | $455 | In Stock | |
25 mg | $753 | In Stock | |
50 mg | $1,060 | In Stock | |
100 mg | $1,430 | In Stock | |
500 mg | $2,860 | In Stock | |
1 mL x 10 mM (in DMSO) | $438 | In Stock |
Description | MIK665 (S-64315) (S-64315) has an inhibitory effect on myeloid leukemia. |
Targets&IC50 | MCL1:1.81 nM |
In vitro | MIK665 (S-64315) had a synergistic effect when combined with ABT-199. Combined treatment with S64315 (0.156-10 μM) and ABT-199 (625 nM) reduced the cell viability of MB2141, MB3616, MB3961, MB4667, A375 and 1205Lu cells. The IC50 of MIK665 interaction with H929 cells was 250 nM[1]. |
Cell Research | MIK665 suppresses H929 cells (IC50: 250 nM). |
Alias | S-64315 |
Molecular Weight | 875.41 |
Formula | C47H44ClFN6O6S |
Cas No. | 1799631-75-6 |
Smiles | COc1ccccc1-c1nccc(COc2ccccc2C[C@@H](Oc2ncnc3sc(c(-c4ccc(OCCN5CCN(C)CC5)c(Cl)c4C)c23)-c2ccc(F)cc2)C(O)=O)n1 |
Relative Density. | 1.324 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 112.5 mg/mL (128.5 mM) H2O: 0.1 mg/mL, insoluble | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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